2754428-18-5
Chemical Structure
6PPD-Q
Synonym(s): 6PPD-Quinone
- CAS No.: 2754428-18-5
- Formula:C18H22N2O2
- Molecular Weight:298.38
IUPAC Name: 2-((4-methylpentan-2-yl)amino)-5-(phenylamino)cyclohexa-2,5-diene-1,4-dione
InChIKey: UBMGKRIXKUIXFQ-UHFFFAOYSA-N
SMILES: O=C1C(NC(C)CC(C)C)=CC(C(NC2=CC=CC=C2)=C1)=O
Biological Activity: 6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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6PPD-Q | 99.77% | 6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders. | ||||||||||||||||||||
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6PPD-quinone-d5 | 99.39% | 6PPD-quinone-d5 is the deuterium labeled 6PPD-quinone. | ||||||||||||||||||||
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6PPD-Q-13C6 | 98.0% | 6PPD-quinone-13C6 is the 13C labeled 6PPD-quinone. | ||||||||||||||||||||
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Keywords
