58-27-5
58-27-5
Chemical Structure
Menadione
Synonym(s): Vitamin K3
- CAS No.: 58-27-5
- Formula:C11H8O2
- Molecular Weight:172.18
IUPAC Name: 2-methylnaphthalene-1,4-dione
InChIKey: MJVAVZPDRWSRRC-UHFFFAOYSA-N
SMILES: O=C1C(C)=CC(C2=C1C=CC=C2)=O
Biological Activity: Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Menadione | 99.82% | Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer. | ||||||||||||||||||||
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Menadione (Standard) | 99.91% | Menadione (Standard) is the analytical standard of Menadione. This product is intended for research and analytical applications. Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer. | ||||||||||||||||||||
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Menadione-d3 | 99.08% | Menadione-d3 is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo. | ||||||||||||||||||||
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Vitamin K3-d8 | 98.90% | Vitamin K3-d8 is the deuterium labeled Vitamin K3. | ||||||||||||||||||||
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2-Chloro-1,4-naphthoquinone | 98.38% | 2-Chloro-1,4-naphthoquinone (chloro-K3) is a vitamin-K-dependent carboxylation antagonist with an IC50 value of 146 μM. 2-Chloro-1,4-naphthoquinone has cytotoxic activity. | ||||||||||||||||||||
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Vitamin impurity 3 (Standard) | ≥98% | Phthiocol (Standard) is the analytical standard of Phthiocol. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Plumbagin | 99.74% | Plumbagin (2-Methyljuglone) is a naphthoquinone isolated from Plumbago zeylanica, exhibits anticancer and antiproliferative activities. | ||||||||||||||||||||
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Lawsone | 99.54% | Lawsone is an orally active naphthoquinone dye that can be isolated from the leaves of Lawsonia inermis. Lawsone can induce apoptosis. Lawsone has antibacterial, antitumor and antioxidant activities. Lawsone can be used in anti-tumor drug research. | ||||||||||||||||||||
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Chimaphilin | 99.80% | Chimaphilin is an IGF-1R inhibitor (IC50: 0.086 μM). Chimaphilin has antifungal, antioxidant and anticancer activities. Chimaphilin inhibits the growth of both drug-sensitive and drug-resistant osteosarcoma cell lines. Chimaphilin can induce cancer cell apoptosis. Chimaphilin is a main component of pyrola. | ||||||||||||||||||||
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Lawsone methyl ether | 99.64% | Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone), isolated from Impatiens balsamina L. and Swertia calycina, exhibits potent antifungal and antibacterial activities. | ||||||||||||||||||||
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1,4-Naphthoquinone | 99.69% | 1,4-Naphthoquinone is an inhibitor with broad-spectrum inhibitory activity targeting DNA polymerase, NF-κB and monoamine oxidase (MAO-A/B), with antibacterial and anti-biofilm efficacy. 1,4-Naphthoquinone is a competitive inhibitor of MAO-B (Ki=1.4 μM) and a non-competitive inhibitor of MAO-A (Ki=7.7 μM). 1,4-Naphthoquinone inhibits DNA polymerase pol α, β, γ, δ, ε, λ with IC50 ranging from 5.57-128 μM. 1,4-Naphthoquinone inhibits tumor cell proliferation, induces apoptosis and necrosis, and has anti-angiogenic and anti-inflammatory activities by inducing oxidative stress, depleting glutathione (GSH), inhibiting DNA polymerase-mediated DNA synthesis and blocking NF-κB nuclear translocation. 1,4-Naphthoquinone can be used in anti-bacterial , anti-tumor and anti-inflammatory studies, including inhibition of melanoma and colon cancer cell growth and endothelial cell function, as well as LPS-induced inflammation models. | ||||||||||||||||||||
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Isoplumbagin | Isoplumbagin is antimicrobial agent. Isoplumbagin exhibits anticancer activity mainly through modulating mitochondrial dynamics and function. | |||||||||||||||||||||
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6-Methyl-1,4-naphthoquinone | 98.49% | 6-Methyl-1,4-naphthoquinone is a kind of biochemical reagent. | ||||||||||||||||||||
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