2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Menadione-d3

Menadione-d3  (Synonyms: Vitamin K3-d3)

Cat. No.: HY-B0332S Purity: 98.08%
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Menadione-d3 is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.

For research use only. We do not sell to patients.

Menadione-d<sub>3</sub> Chemical Structure

Menadione-d3 Chemical Structure

CAS No. : 5172-16-7

Size Price Stock Quantity
5 mg USD 200 In-stock
10 mg USD 320 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Menadione-d3:

Menadione-d3 Related Antibodies

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Description

Menadione-d3 is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Menadione-d3 Related Antibodies
Molecular Weight

175.20

Formula

C11H5D3O2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C(C([2H])([2H])[2H])=CC(C2=C1C=CC=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (713.47 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7078 mL 28.5388 mL 57.0776 mL
5 mM 1.1416 mL 5.7078 mL 11.4155 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.7078 mL 28.5388 mL 57.0776 mL 142.6941 mL
5 mM 1.1416 mL 5.7078 mL 11.4155 mL 28.5388 mL
10 mM 0.5708 mL 2.8539 mL 5.7078 mL 14.2694 mL
15 mM 0.3805 mL 1.9026 mL 3.8052 mL 9.5129 mL
20 mM 0.2854 mL 1.4269 mL 2.8539 mL 7.1347 mL
25 mM 0.2283 mL 1.1416 mL 2.2831 mL 5.7078 mL
30 mM 0.1903 mL 0.9513 mL 1.9026 mL 4.7565 mL
40 mM 0.1427 mL 0.7135 mL 1.4269 mL 3.5674 mL
50 mM 0.1142 mL 0.5708 mL 1.1416 mL 2.8539 mL
60 mM 0.0951 mL 0.4756 mL 0.9513 mL 2.3782 mL
80 mM 0.0713 mL 0.3567 mL 0.7135 mL 1.7837 mL
100 mM 0.0571 mL 0.2854 mL 0.5708 mL 1.4269 mL
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Menadione-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Menadione-d35172-16-7Vitamin K3-d3Endogenous MetaboliteInhibitorinhibitorinhibit

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