2. Isotope-Labeled Compounds
  3. Internal Standard for Clinical Mass Spectrometry
  4. Vitamins

Vitamins

Vitamins are one of the six essential nutrients needed by the human body (vitamins, proteins, fats, minerals, water and carbohydrates) for normal functioning. These are micronutrients that play an important role in the growth, metabolism, and development of the human body. Most vitamins cannot be synthesized in the body or not in sufficient quantities and must be obtained through diet and other means. Although the daily requirement of the human body for vitamins is very small, once deficient, it can cause a range of symptoms associated with "vitamin deficiency". Vitamin deficiency can cause a number of diseases such as rickets (vitamin D deficiency), scurvy (vitamin C deficiency), angular cheilitis (vitamin B deficiency), and xerophthalmia (vitamin A deficiency). Different vitamins play a variety of roles in the body. It is difficult to monitor human body vitamin levels or identify a potential vitamin deficiency. The isotope labeled vitamins play an important role in the detection of vitamin content in the human body. Isotope-labeled compounds are used as internal standards to make the quantification more accurate and sensitive in clinical mass spectrometry.

Vitamins (109):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0150S
    Nicotinamide-d4 347841-88-7 99.97%
    Nicotinamide-d4 is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
    Nicotinamide-d<sub>4</sub>
  • HY-15331
    Vitamin D3-d6 118584-54-6 98.47%
    Vitamin D3-d6 (Cholecalciferol-d6 ) is the deuterium labeled Vitamin D3 (HY-15398) . Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
    Vitamin D3-d<sub>6</sub>
  • HY-76814
    Calcitriol-d6 78782-99-7 99.27%
    Calcitriol-d6 is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR).
    Calcitriol-d<sub>6</sub>
  • HY-N0682S3
    Pyridoxine-13C4 hydrochloride 98.69%
    Pyridoxine-13C4 (hydrochloride) is the 13C-labeled Pyridoxine (hydrochloride). Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine-<sup>13</sup>C<sub>4</sub> hydrochloride
  • HY-13332
    Calcifediol-d6 78782-98-6 99.09%
    Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand.
    Calcifediol-d<sub>6</sub>
  • HY-B0166S
    L-Ascorbic acid-13C6 1354064-87-1 99.90%
    L-Ascorbic acid-13C6 is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells.
    L-Ascorbic acid-<sup>13</sup>C<sub>6</sub>
  • HY-B0143S2
    Niacin-d4 66148-15-0 99.71%
    Niacin-d4 is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.
    Niacin-d<sub>4</sub>
  • HY-N7148S
    α-Vitamin E-d6 113892-08-3 99.53%
    α-Vitamin E-d6 is the deuterium labeled α-Vitamin E.
    α-Vitamin E-d<sub>6</sub>
  • HY-14649S4
    Retinoic acid-d5 78996-15-3 99.07%
    Retinoic acid-d5 is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
    Retinoic acid-d<sub>5</sub>
  • HY-B0166S6
    L-Ascorbic acid-d2 82977-10-4 99.90%
    L-Ascorbic acid-d2 is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla
    L-Ascorbic acid-d<sub>2</sub>
  • HY-N0157S1
    Orotic acid-13C,15N2 monohydrate 1346602-15-0 99.93%
    Orotic acid-13C,15N2 (monohydrate) is the 13C and 15N labeled Orotic acid. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats.
    Orotic acid-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub> monohydrate
  • HY-15398S3
    Vitamin D3-d3 80666-48-4 98.45%
    Vitamin D3-d3 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
    Vitamin D3-d<sub>3</sub>
  • HY-N0411S1
    β-Carotene-d8 53163-44-3
    β-Carotene-d8 is the deuterium labeled β-Carotene (HY-N0411).
    β-Carotene-d<sub>8</sub>
  • HY-15329
    Maxacalcitol-d6 2070009-38-8
    Maxacalcitol-d66 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.
    Maxacalcitol-d<sub>6</sub>
  • HY-141923S
    Pyridoxamine-d3 dihydrochloride 1173023-45-4 99.33%
    Pyridoxamine-d3 (dihydrochloride) is the deuterium labeled Pyridoxamine dihydrochloride.
    Pyridoxamine-d<sub>3</sub> dihydrochloride
  • HY-B0143S3
    Niacin-13C6 1189954-79-7 99.90%
    Niacin-13C6 is the 13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.
    Niacin-<sup>13</sup>C<sub>6</sub>
  • HY-B0430S
    Pantothenic acid-13C3,15N hemicalcium 356786-94-2 99.3%
    Pantothenic acid-13C3,15N (hemicalcium) is the 13C-labeled and 15N-labeled D-Pantothenic acid. D-Pantothenic acid is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism.
    Pantothenic acid-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N hemicalcium
  • HY-B0456S3
    Riboflavin-d3 99.90%
    Riboflavin-d3 is the deuterium labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
    Riboflavin-d<sub>3</sub>
  • HY-N0682S1
    Pyridoxine-d2 hydrochloride 5027-82-7 98.89%
    Pyridoxine-d2 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
    Pyridoxine-d<sub>2</sub> hydrochloride
  • HY-144243S
    Vitamin B5-d4 calcium 99.17%
    Vitamin B5-d4 (calcium) is the deuterium labeled Vitamin B5 calcium.
    Vitamin B5-d<sub>4</sub> calcium