Calcitriol-d6
Based on 1 Customer Validation
Calcitriol-d6 is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR).
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- Purity: 99.27%
- CAS No.: 78782-99-7
- 화학식: C27H38D6O3
- 분자량:422.67
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보관:Powder -20°C, 3 years , 4°C, 2 years
* The compound is unstable in solutions, freshly prepared is recommended.
Biological Activity
Calcitriol-d6 can be used as an internal standard for the quantitative analysis of Calcitriol (HY-10002) in plasma[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 78782-99-7
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Unlabeled Cas 32222-06-3
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Appearance Solid
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분자량 422.67
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화학식 C27H38D6O3
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Color White to off-white
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SMILES
C=C1/C(C[C@H](C[C@@H]1O)O)=C\C=C2CCC[C@]3(C)[C@@H]([C@@H](CCCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O)C)CC[C@@]/23[H]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years * The compound is unstable in solutions, freshly prepared is recommended.
용액&용해도
DMSO : 50 mg/mL (118.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (605 KB)
- English - EN (605 KB)
- Français - FR (605 KB)
- Deutsch - DE (605 KB)
- Norwegian - NO (605 KB)
- Español - ES (605 KB)
- Swedish - SV (605 KB)
- Italian - IT (605 KB)
- Korean - KR (605 KB)
- Portuguese - PT (605 KB)
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Handling Instructions (2659 KB)
References
[1]. Nair SN, et al. A liquid chromatography/electrospray ionization tandem mass spectrometric method for quantification of asiatic acid from plasma: application to pharmacokinetic study in rats. Rapid Commun Mass Spectrom. 2012 Sep 15;26(17):1899-908. [Content Brief]
[2]. Canalejo, et al. The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004) [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3659 mL | 11.8296 mL | 23.6591 mL | 59.1478 mL |
| 5 mM | 0.4732 mL | 2.3659 mL | 4.7318 mL | 11.8296 mL | |
| 10 mM | 0.2366 mL | 1.1830 mL | 2.3659 mL | 5.9148 mL | |
| 15 mM | 0.1577 mL | 0.7886 mL | 1.5773 mL | 3.9432 mL | |
| 20 mM | 0.1183 mL | 0.5915 mL | 1.1830 mL | 2.9574 mL | |
| 25 mM | 0.0946 mL | 0.4732 mL | 0.9464 mL | 2.3659 mL | |
| 30 mM | 0.0789 mL | 0.3943 mL | 0.7886 mL | 1.9716 mL | |
| 40 mM | 0.0591 mL | 0.2957 mL | 0.5915 mL | 1.4787 mL | |
| 50 mM | 0.0473 mL | 0.2366 mL | 0.4732 mL | 1.1830 mL | |
| 60 mM | 0.0394 mL | 0.1972 mL | 0.3943 mL | 0.9858 mL | |
| 80 mM | 0.0296 mL | 0.1479 mL | 0.2957 mL | 0.7393 mL | |
| 100 mM | 0.0237 mL | 0.1183 mL | 0.2366 mL | 0.5915 mL |