(Sar1,Ile4,8)-Angiotensin II
Based on 1 Customer Validation
(Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β.
For research use only. We do not sell to patients.
- Purity: 98.23%
- CAS No.: 185461-45-4
- Formula: C43H75N13O9
- Molecular Weight:918.14
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Angiotensin Receptor Isoforms
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Biological Activity
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Angiotensin II Type 1 |
Chemical Information
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CAS No. 185461-45-4
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Appearance Solid
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Molecular Weight 918.14
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Formula C43H75N13O9
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Color White to off-white
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Sequence
{Sar}-Arg-Val-Ile-Ile-His-Pro-Ile
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Sequence Shortening
{Sar}-RVIIHPI
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
H2O : 100 mg/mL (108.92 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.0892 mL | 5.4458 mL | 10.8916 mL | 27.2290 mL |
| 5 mM | 0.2178 mL | 1.0892 mL | 2.1783 mL | 5.4458 mL | |
| 10 mM | 0.1089 mL | 0.5446 mL | 1.0892 mL | 2.7229 mL | |
| 15 mM | 0.0726 mL | 0.3631 mL | 0.7261 mL | 1.8153 mL | |
| 20 mM | 0.0545 mL | 0.2723 mL | 0.5446 mL | 1.3614 mL | |
| 25 mM | 0.0436 mL | 0.2178 mL | 0.4357 mL | 1.0892 mL | |
| 30 mM | 0.0363 mL | 0.1815 mL | 0.3631 mL | 0.9076 mL | |
| 40 mM | 0.0272 mL | 0.1361 mL | 0.2723 mL | 0.6807 mL | |
| 50 mM | 0.0218 mL | 0.1089 mL | 0.2178 mL | 0.5446 mL | |
| 60 mM | 0.0182 mL | 0.0908 mL | 0.1815 mL | 0.4538 mL | |
| 80 mM | 0.0136 mL | 0.0681 mL | 0.1361 mL | 0.3404 mL | |
| 100 mM | 0.0109 mL | 0.0545 mL | 0.1089 mL | 0.2723 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
(Sar1,Ile4,8)-Angiotensin II Related Classifications
HY-P4685 Related Classifications
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