1. Protein Tyrosine Kinase/RTK
  2. Insulin Receptor

AGL-2263 

Cat. No.: HY-112720
Handling Instructions

AGL-2263 is an insulin receptor (IR) blocker.

For research use only. We do not sell to patients.

AGL-2263 Chemical Structure

AGL-2263 Chemical Structure

CAS No. : 638213-98-6

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

AGL-2263 is an insulin receptor (IR) blocker.

IC50 & Target

Insulin receptor[1].

In Vitro

AGL-2263 is an insulin receptor (IR) blocker[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1030 mL 15.5149 mL 31.0299 mL
5 mM 0.6206 mL 3.1030 mL 6.2060 mL
10 mM 0.3103 mL 1.5515 mL 3.1030 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Cell Assay
[1]

Trophoblast cells are prepared from normal or GDM placentas. They are incubated in the presence of stimulants, insulin (100 nM) or both insulin and AGL-2263 (AGL, 5 μM) IR blocker, together for 24 hr[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

322.27

Formula

C₁₇H₁₀N₂O₅

CAS No.

638213-98-6

SMILES

O=C(C1=CC(O)=C(O)C=C1)/C(C#N)=C/C2=CC=C(OC3=O)C(N3)=C2

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
AGL-2263
Cat. No.:
HY-112720
Quantity:

AGL-2263

Cat. No.: HY-112720