β-Actin
Actin exists in three major isoforms, including α-, β-, and γ-actin. β-Aactin is primarily found in nonmuscle cells (e.g., β-cytoplasmic). β-Actin is a highly conserved cytoskeletal protein found in nearly all eukaryotic cells. It is an essential structural component of the cytoskeleton, playing a crucial role in cell motility, division, structural integrity, and intracellular signaling. β-Actin is often used in Western blotting as a loading control, to normalize total protein amounts and check for eventual protein degradation in the samples.
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β-Actin Related Products (1)
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β-actin-IN-1
0 ImagesCat. No.: HY-184235β-actin-IN-1 is a selective and covalent β-actin polymerization inhibitor. β-actin-IN-1 targets Cys272 of β-actin and shows selectivity over α-actin and γ-actin. β-actin-IN-1 inhibits β-actin polymerization and disrupts the actin cytoskeleton in cancer cells, leading to cell migration inhibition as well as cell death. β-actin-IN-1 can be used for the study of osteosarcoma.
