β-Actin

Actin exists in three major isoforms, including α-, β-, and γ-actin. β-Aactin is primarily found in nonmuscle cells (e.g., β-cytoplasmic). β-Actin is a highly conserved cytoskeletal protein found in nearly all eukaryotic cells. It is an essential structural component of the cytoskeleton, playing a crucial role in cell motility, division, structural integrity, and intracellular signaling. β-Actin is often used in Western blotting as a loading control, to normalize total protein amounts and check for eventual protein degradation in the samples.