Dehydrotumulosic acid
Based on 1 Customer Validation
Dehydrotumulosic acid is one of the effective constituents of Poria cocos. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body.
For research use only. We do not sell to patients.
- Purity: 99.06%
- CAS No.: 6754-16-1
- Formula: C31H48O4
- Molecular Weight:484.71
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
>40 μM
Compound: 10
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Antiproliferative activity against human CCRF-CEM cells after 72 hrs by MTT assay
Antiproliferative activity against human CCRF-CEM cells after 72 hrs by MTT assay
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[PMID: 27808511] |
| HL-60 | IC50 |
>40 μM
Compound: 10
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Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
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[PMID: 27808511] |
| K562 | IC50 |
>40 μM
Compound: 10
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Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
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[PMID: 27808511] |
| MOLT-4 | IC50 |
>40 μM
Compound: 10
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Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay
Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay
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[PMID: 27808511] |
Chemical Information
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CAS No. 6754-16-1
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Appearance Solid
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Molecular Weight 484.71
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Formula C31H48O4
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Color White to off-white
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SMILES
C[C@]12[C@@]([C@]([C@H](C(O)=O)CCC(C(C)C)=C)([H])[C@H](O)C1)(CC=C3C2=CC[C@]4([H])[C@@]3(CC[C@H](O)C4(C)C)C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 33.33 mg/mL (68.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0631 mL | 10.3154 mL | 20.6309 mL | 51.5772 mL |
| 5 mM | 0.4126 mL | 2.0631 mL | 4.1262 mL | 10.3154 mL | |
| 10 mM | 0.2063 mL | 1.0315 mL | 2.0631 mL | 5.1577 mL | |
| 15 mM | 0.1375 mL | 0.6877 mL | 1.3754 mL | 3.4385 mL | |
| 20 mM | 0.1032 mL | 0.5158 mL | 1.0315 mL | 2.5789 mL | |
| 25 mM | 0.0825 mL | 0.4126 mL | 0.8252 mL | 2.0631 mL | |
| 30 mM | 0.0688 mL | 0.3438 mL | 0.6877 mL | 1.7192 mL | |
| 40 mM | 0.0516 mL | 0.2579 mL | 0.5158 mL | 1.2894 mL | |
| 50 mM | 0.0413 mL | 0.2063 mL | 0.4126 mL | 1.0315 mL | |
| 60 mM | 0.0344 mL | 0.1719 mL | 0.3438 mL | 0.8596 mL |
Dehydrotumulosic acid Related Classifications
HY-N2499 Related Classifications
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