2. Natural Products
  3. Terpenoids
  4. Triterpenes

Triterpenes

Triterpenes (1570):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-13067
    Celastrol 34157-83-0 99.90%
    Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. In addition, Celastrol is also an antibiotic with potent antimicrobial activity against standard and clinical methicillin-resistant Staphylococcus aureus (MRSA) strains, inducing oxidative stress and inhibiting DNA synthesis by binding to P5CDH.
    Celastrol
  • HY-N0184
    Glycyrrhizic acid 1405-86-3 99.84%
    Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.
    Glycyrrhizic acid
  • HY-N0431
    Astragaloside IV 84687-43-4 99.93%
    Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
    Astragaloside IV
  • HY-N0140
    Ursolic acid 77-52-1 99.02%
    Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.
    Ursolic acid
  • HY-100597
    Saponins 8047-15-2 98.36%
    Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi.
    Saponins
  • HY-N19939
    Saponarioside D 223376-66-7
    Saponarioside D is a triterpenoid saponin found in whole plants and roots of Saponaria officinalis L..
    Saponarioside D
  • HY-N19933
    cis-3-O-Hydroxycinnamoyl-ursolic acid 331243-42-6
    cis-3-O-Hydroxycinnamoyl-ursolic acid is a cis-cinnamic acid ester derivative. cis-3-O-Hydroxycinnamoyl-ursolic acid exhibits no α-glucosidase inhibitory activity.
    cis-3-O-Hydroxycinnamoyl-ursolic acid
  • HY-N19887
    Periandrin I 73565-59-0
    Periandrin I is a triterpenoid glycoside. Periandrin I can be isolated from the roots of Periandra dulcis. Periandrin I acts as a sweetener, with a sweetness intensity comparable to that of Periandrin II, Periandrin IV and Glycyrrhizin (HY-N0184).
    Periandrin I
  • HY-N0156
    Oleanolic acid 508-02-1 98.0%
    Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
    Oleanolic acid
  • HY-N0439
    Asiaticoside 16830-15-2 99.67%
    Asiaticoside, a trisaccaride triterpene from Centella asiatica, suppresses TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts; Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties.
    Asiaticoside
  • HY-10529
    Betulinic acid 472-15-1 99.88%
    Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties. Betulinic acid can cross the blood-brain barrier.
    Betulinic acid
  • HY-N0045
    Ginsenoside Rg1 22427-39-0 99.88%
    Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.
    Ginsenoside Rg1
  • HY-N0603
    20(S)-Ginsenoside Rg3 14197-60-5 99.82%
    20(S)-Ginsenoside Rg3 is the main component of Panax ginseng C. A. Meyer. Ginsenoside Rg3 inhibits Na+ and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. 20(S)-Ginsenoside Rg3 also inhibits Aβ levels, NF-κB activity, and COX-2 expression.
    20(S)-Ginsenoside Rg3
  • HY-113342
    7-Ketocholesterol 566-28-9 99.87%
    7-Ketocholesterol is an oxidation product of cholesterol, widely present in atherosclerotic plaques, and has a stronger atherogenic effect than cholesterol. 7-Ketocholesterol can inhibit the rate-limiting enzymes involved in bile acid and cholesterol synthesis, such as cholesterol 7α-hydroxylase and HMG-CoA reductase. 7-Ketocholesterol exhibits pro-inflammatory effects both in vivo and in vitro and can induce cell apoptosis (apoptosis).
    7-Ketocholesterol
  • HY-N0039
    Ginsenoside Rb1 41753-43-9 99.75%
    Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .
    Ginsenoside Rb1
  • HY-107738
    Guggulsterone 95975-55-6 99.83%
    Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt. Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC50s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively.
    Guggulsterone
  • HY-N0180
    18β-Glycyrrhetinic acid 471-53-4 99.88%
    18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
    18β-Glycyrrhetinic acid
  • HY-N1214
    Squalene 111-02-4 98.0%
    Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity.
    Squalene
  • HY-N0605
    Ginsenoside Rh2 78214-33-2 99.28%
    Ginsenoside Rh2 (20(S)-Ginsenoside Rh2) induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner.
    Ginsenoside Rh2
  • HY-W020033
    Lanosterol 79-63-0 99.97%
    Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases.
    Lanosterol