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Polyporaceae

 

Polyporaceae (91):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1447
    Ganoderic acid A 81907-62-2 99.84%
    Ganoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.
    Ganoderic acid A
  • HY-N0371
    Pachymic acid 29070-92-6 99.94%
    Pachymic acid is a lanostrane-type triterpenoid from P. cocos. Pachymic acid inhibits Akt and ERK signaling pathways.
    Pachymic acid
  • HY-N2995
    Poricoic acid A 137551-38-3 99.19%
    Poricoic acid A can be isolated from Poria cocos. Poricoic acid A is an orally active anti-tumor agent. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. Poricoic acid A also attenuatea fibroblast activation and abnormal extracellular matrix remodeling in renal fibrosis by activating AMPK and inhibiting Smad3. Poricoic acid A significantly reduces the magnitude of rise in serum creatinine and urea levels in rat model when combined with Melatonin. Poricoic acid A ameliorates renal fibrosis and podocyte injury by attenuating oxidative stress and inflammation through regulating NF-κB and Nrf2 in IRI rodent model in combination with Melatonin.
    Poricoic acid A
  • HY-N1511
    Ganoderic acid D 108340-60-9 99.89%
    Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. Ganoderic acid D induces HeLa human cervical carcinoma apoptosis.
    Ganoderic acid D
  • HY-N2499
    Dehydrotumulosic acid 6754-16-1 99.06%
    Dehydrotumulosic acid is one of the effective constituents of Poria cocos. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body.
    Dehydrotumulosic acid
  • HY-134802
    2-Hydroxyhexacosanoic acid 14176-13-7
    2-Hydroxyhexacosanoic acid is a hydroxylated fatty acid. 2-Hydroxyhexacosanoic acid can be obtained from C26 acids by the 2-hydroxylase of Candida utilis.
    2-Hydroxyhexacosanoic acid
  • HY-N17421
    (7β,22E)-7,8-Epoxyergosta-4,22-diene-3,6-dione 2568879-54-7
    (7β,22E)-7,8-Epoxyergosta-4,22-diene-3,6-dione (Compound 1) is a steroidal compound. It can be extracted from Ganoderma lingzhi. (7β,22E)-7,8-Epoxyergosta-4,22-diene-3,6-dione exhibits anticancer activity against non-small cell lung cancer and breast cancer.
    (7β,22E)-7,8-Epoxyergosta-4,22-diene-3,6-dione
  • HY-N16673
    Fornicin A 908588-41-0
    Fornicin A is a natural phenolic compound.
    Fornicin A
  • HY-120140
    Ganoderic acid DM 173075-45-1 99.87%
    Ganoderic acid DM, a natural triterpenoid isolated from Ganoderma lucidum, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Ganoderic acid DM as a specific inhibitor of osteoclastogenesis.
    Ganoderic acid DM
  • HY-N6036
    Ganoderic acid F 98665-15-7 99.70%
    Ganoderic acid F is a ganoderic acid. Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum stress.
    Ganoderic acid F
  • HY-N1517
    Ganoderic acid C2 103773-62-2 99.72%
    Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 is the inhibitor for aldose reductase with an IC50 of 43.8 µM.
    Ganoderic acid C2
  • HY-N4124
    Poricoic acid B 137551-39-4 98.60%
    Poricoic acid B is a triterpenoid compound that can be isolated from Poria cocos. Poricoic acid B inhibits intracellular lipid accumulation and reduces the levels of hepatocyte injury markers. Poricoic acid B inhibits the production of NO, TNF-α, IL-1β and IL-6, thereby exerting anti-inflammatory activity. Poricoic acid B can be used in the research of metabolic dysfunction-associated fatty liver disease and inflammatory diseases[3].
    Poricoic acid B
  • HY-N9366
    Tumulosic acid 508-24-7 98.66%
    Tumulosic acid, a triterpenoid, inhibits KLK5 protease activity (IC50= 14.84 μM). Tumulosic acid suppresses the proteolytic processing of LL-37 in keratinocytes at ≤10 μM.
    Tumulosic acid
  • HY-N2993
    Polyporenic acid C 465-18-9 ≥99.0%
    Polyporenic acid C is a lanostane-type triterpenoid. Polyporenic acid C can be isolated from Poria cocos. Polyporenic acid C causes the cleavage of caspase-8 and caspase-3, as well as the cleavage of PARP. Polyporenic acid C reduces the phosphorylation level of Akt (Ser473), increases the phosphorylation of PTEN and p53 (Ser15), and activates JNK. Polyporenic acid C induces Apoptosis. Polyporenic acid C shows anticancer activity against non-small cell lung cancer.
    Polyporenic acid C
  • HY-N1506
    Ganodermanontriol 106518-63-2
    Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity.
    Ganodermanontriol
  • HY-N2991
    Dehydropachymic acid 77012-31-8 99.95%
    Dehydropachymic acid is one of the major triterpenes isolated from Poria cocos. Dehydropachymic acid is more effective in autophagy-lysosome pathway (ALP) impaired cells rather than normal cells.
    Dehydropachymic acid
  • HY-N2006
    Ganoderic acid B 81907-61-1 99.60%
    Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM).
    Ganoderic acid B
  • HY-N2458
    Ganoderic acid G 98665-22-6 99.93%
    Ganoderic acid G is a highly oxidized lanostane-type triterpenoid compound. Ganoderic acid G can be isolated from the fungus Ganoderma lucidum.
    Ganoderic acid G
  • HY-N7693
    Polyporusterone B 141360-89-6 99.24%
    Polyporusterone B is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone B has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis).
    Polyporusterone B
  • HY-N13243
    Reishi Mushroom Extract
    Reishi Mushroom Extract is the extract of Reishi Mushroom, with content of 10% -50% Polysaccharide.
    Reishi Mushroom Extract