137551-39-4
Chemical Structure
Poricoic acid B
- CAS No.: 137551-39-4
- Formula:C30H44O5
- Molecular Weight:484.67
IUPAC Name: (R)-2-((2R,3R,3aR,6S,7S,9bR)-6-(2-carboxyethyl)-2-hydroxy-3a,6,9b-trimethyl-7-(prop-1-en-2-yl)-2,3,3a,4,6,7,8,9b-octahydro-1H-cyclopenta[a]naphthalen-3-yl)-6-methylhept-5-enoic acid
InChIKey: NXAZWYWJZDFISF-KXGBKNTBSA-N
SMILES: O=C(O)CC[C@@]1(C)[C@H](C(C)=C)CC=C2[C@]3(C)C[C@@H](O)[C@H]([C@H](C(O)=O)CC/C=C(C)\C)[C@@]3(C)CC=C21
Biological Activity: Poricoic acid B is a triterpenoid compound that can be isolated from Poria cocos. Poricoic acid B inhibits intracellular lipid accumulation and reduces the levels of hepatocyte injury markers. Poricoic acid B inhibits the production of NO, TNF-α, IL-1β and IL-6, thereby exerting anti-inflammatory activity. Poricoic acid B can be used in the research of metabolic dysfunction-associated fatty liver disease and inflammatory diseases[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Poricoic acid B | 98.60% | Poricoic acid B is a triterpenoid compound that can be isolated from Poria cocos. Poricoic acid B inhibits intracellular lipid accumulation and reduces the levels of hepatocyte injury markers. Poricoic acid B inhibits the production of NO, TNF-α, IL-1β and IL-6, thereby exerting anti-inflammatory activity. Poricoic acid B can be used in the research of metabolic dysfunction-associated fatty liver disease and inflammatory diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.92
HY-N9527Poricoic acid BM -
Similarity Score 0.88
HY-N2995Poricoic acid A -
Similarity Score 0.82
HY-N8430Poricoic acid AM -
Similarity Score 0.80
HY-N8978Poricoic acid AE -
Similarity Score 0.79
HY-N10071Poricoic acid G -
Similarity Score 0.75
HY-N299016α-Hydroxydehydrotrametenolic acid -
Similarity Score 0.73
HY-N953316R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid -
Similarity Score 0.72
HY-N29893-O-Acetyl-16α-hydroxydehydrotrametenolic acid -
Similarity Score 0.71
HY-N11656Poricoic acid H -
Explore the MedChemAI to find more analogs
References
- [1]. He J, et al. Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway. Front. Pharmacol. 13:1007274.
- [2]. Dong H, et al. Enrichment and separation of antitumor triterpene acids from the epidermis of Poria cocos by pH-zone-refining counter-current chromatography and conventional high-speed counter-current chromatography. J Sep Sci. 2015;38(11):1977-1982. [Content Brief]
