Poricoic acid AM
Based on 1 Customer Validation
Poricoic acid AM is a triterpenoid with ant-tumor activities.
For research use only. We do not sell to patients.
- Purity: 99.25%
- CAS No.: 151200-92-9
- Formula: C32H48O5
- Molecular Weight:512.72
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
15.9 μM
Compound: 9
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Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
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[PMID: 19746919] |
Chemical Information
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CAS No. 151200-92-9
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Appearance Solid
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Molecular Weight 512.72
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Formula C32H48O5
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Color White to off-white
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SMILES
C[C@]12[C@@]([C@@]([C@@H](C1)O)([H])[C@H](C(O)=O)CCC(C(C)C)=C)(CC=C3C2=CC[C@H]([C@]3(C)CCC(OC)=O)C(C)=C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (97.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9504 mL | 9.7519 mL | 19.5038 mL | 48.7596 mL |
| 5 mM | 0.3901 mL | 1.9504 mL | 3.9008 mL | 9.7519 mL | |
| 10 mM | 0.1950 mL | 0.9752 mL | 1.9504 mL | 4.8760 mL | |
| 15 mM | 0.1300 mL | 0.6501 mL | 1.3003 mL | 3.2506 mL | |
| 20 mM | 0.0975 mL | 0.4876 mL | 0.9752 mL | 2.4380 mL | |
| 25 mM | 0.0780 mL | 0.3901 mL | 0.7802 mL | 1.9504 mL | |
| 30 mM | 0.0650 mL | 0.3251 mL | 0.6501 mL | 1.6253 mL | |
| 40 mM | 0.0488 mL | 0.2438 mL | 0.4876 mL | 1.2190 mL | |
| 50 mM | 0.0390 mL | 0.1950 mL | 0.3901 mL | 0.9752 mL | |
| 60 mM | 0.0325 mL | 0.1625 mL | 0.3251 mL | 0.8127 mL | |
| 80 mM | 0.0244 mL | 0.1219 mL | 0.2438 mL | 0.6095 mL |