106518-63-2
Chemical Structure
Ganodermanontriol
- CAS No.: 106518-63-2
- Formula:C30H48O4
- Molecular Weight:472.70
IUPAC Name: (5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-((2R,5S,6R)-5,6,7-trihydroxy-6-methylheptan-2-yl)-1,2,4,5,6,10,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: KASALCUNLBTNAA-LIPCCPSCSA-N
SMILES: CC1(C)C(CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C)CC[C@H](O)[C@](C)(O)CO)CC[C@](C)4C3=CC[C@@]12[H])=O
Biological Activity: Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity[1][2].
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Ganodermanontriol | 97.42% | Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity. | ||||||||||||||||||||
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Ganodermanontriol (Standard) | ≥98% | Karbutilate (Standard) is the analytical standard of Karbutilate. This product is intended for research and analytical applications. Karbutilate (NIA-11092) is a nonselective soil-active herbicide which is used to kill one-leaf pinyon saplings. | ||||||||||||||||||||
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- [1]. Ha do T, et al. In vitro and in vivo hepatoprotective effect of ganodermanontriol against t-BHP-induced oxidative stress. Ethnopharmacol. 2013 Dec 12;150(3):875-85. [Content Brief]
- [2]. Kennedy EM, et al. Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols. J Nat Prod. 2011 Nov 28;74(11):2332-7. [Content Brief]
