1. Terpenoids and Glycosides

Ganoderic acid A 

Cat. No.: HY-N1447 Purity: 98.94%
Data Sheet SDS Handling Instructions

Ganoderic acid can Inhibitt of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.

For research use only. We do not sell to patients.
Ganoderic acid A Chemical Structure

Ganoderic acid A Chemical Structure

CAS No. : 81907-62-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO $205 In-stock
1 mg $80 In-stock
5 mg $180 In-stock
10 mg $230 In-stock
25 mg $500 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

Ganoderic acid can Inhibitt of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS. In vitro: A lower doses of Ganoderic acid enhance HLA class II-mediated antigen presentation and CD4+ T cell recognition of lymphoma. [1] ganoderic acid A promots cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression. [2] Ganoderic acid A inhibits proliferation, viability, ROS, DPPH, and analyzed the expression of SOD1, SOD2, and SOD3 by Real time PCR in a PC-3 cell in a dose-dependent manner.[3] GA-A effectively inhibites the proliferation of human osteosarcoma HOS and MG-63 cells in a dose-dependent manner, and induced obvious cell apoptosis in both cells.[4] In vivo: Ganoderic acid -treatment significantly prolonged survival of EL4 challenged mice and decreased tumor metastasis to the liver.[1]

References
Molecular Weight

516.67

Formula

C₃₀H₄₄O₇

CAS No.

81907-62-2

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 29 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Ganoderic acid A
Cat. No.:
HY-N1447
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