1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. Sirtuin
  4. SIRT3 Isoform

SIRT3

 

SIRT3 Related Products (18):

Cat. No. Product Name Effect Purity
  • HY-123033A
    Nicotinamide riboside chloride
    Activator 99.53%
    Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3.
  • HY-108331
    3-TYP
    Inhibitor 99.93%
    3-TYP is a selective SIRT3 inhibitor, with an IC50 of 16 nM, more potent over SIRT1 (IC50=88 nM), SIRT2 (IC50=92 nM).
  • HY-100578
    AGK2
    Inhibitor 99.62%
    AGK2 is a selective SIRT2 inhibitor with an IC50 of 3.5 μM.
  • HY-15510
    Tenovin-6
    Inhibitor 98.67%
    Tenovin-6, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity.
  • HY-N1511
    Ganoderic acid D
    Activator 99.81%
    Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum.
  • HY-150727
    SIRT5 inhibitor 4
    Inhibitor
    SIRT5 inhibitor 4 (compound 11) is a potent, selective SIRT5 inhibitor with IC50 values of 26.4 and >400μM for SIRT5 and other SIRT subtype, respectively.
  • HY-146013
    Sirt1/2-IN-1
    Inhibitor
    Sirt1/2-IN-1 (Compound 7) is a SIRT1 and SIRT2 inhibitor with IC50 values of 1.81, 2.10 and 20.5 µg/mL against SIRT1, SIRT2 and SIRT3, respectively.
  • HY-151519
    SIRT2-IN-9
    Inhibitor 99.45%
    SIRT2-IN-9 (compound 12) is a selective inhibitor of SRIT2 with an IC50 value of 1.3 μM.
  • HY-N6675
    Gardenia yellow
    Activator
    Gardenia yellow is an active member of crocin, increases mRNA expression of SIRT3, and acts as an orally active antidepressant agent.
  • HY-16616
    SIRT-IN-2
    Inhibitor 98.56%
    SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 μM, respectively.
  • HY-15510B
    Tenovin-6 Hydrochloride
    Inhibitor ≥98.0%
    Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity.
  • HY-136199
    SIRT1-IN-1
    Inhibitor 98.01%
    SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM.
  • HY-123033
    Nicotinamide riboside
    Activator
    Nicotinamide riboside, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3.
  • HY-111303
    CHIC35
    Inhibitor
    CHIC35, an analog of EX-527, is a potent and selective inhibitor of SIRT1 (IC50=0.124 µM).
  • HY-16615
    SIRT-IN-1
    Inhibitor 98.58%
    SIRT-IN-1 is a potent inhibitor of SIRT1/2/3, with IC50s of 15, 10, 33 μM, respectively.
  • HY-123033B
    Nicotinamide riboside tartrate
    Activator
    Nicotinamide riboside tartrate, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3.
  • HY-123033C
    Nicotinamide riboside malate
    Activator
    Nicotinamide riboside malate, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3.
  • HY-111329
    JGB1741
    Inhibitor 99.05%
    JGB1741 (ILS-JGB-1741) is a potent and specific SIRT1 activity inhibitor with an IC50 of ∼15 μM.