ERK Inhibitors

ERK

ERK1

ERK2

ERK5

ERK8

ERK Inhibitors, Agonists, Activators, Modulators, Inducers & Degraders

Product Name	ERK	ERK1	ERK2	ERK5	ERK8	Purity
Yoda 1		ERK1	ERK2			99.97%
PD98059		ERK1	ERK2			99.94%
SCH772984		ERK1, IC₅₀: 4 nM	ERK2, IC₅₀: 1 nM			99.83%
FZ1 peptide		ERK1	ERK2			99.92%
Tauroursodeoxycholate	ERK					99.93%
β-Glycerophosphate disodium salt pentahydrate		ERK1	ERK2			99.99%
Astragaloside IV		ERK1	ERK2			99.93%
Ulixertinib			ERK2, IC₅₀: 0.3 nM (at K_M ATP (60 μM))			99.95%
TBHQ	ERK					99.88%
Honokiol		ERK1	ERK2			99.90%
C16-PAF	ERK					99.86%
Tauroursodeoxycholate sodium	ERK					98.40%
β-Glycerophosphate disodium salt hydrate		ERK1	ERK2			99.92%
Lysophosphatidylcholines		ERK1	ERK2			99.9%
Desipramine hydrochloride		ERK1	ERK2			99.76%
Piperlongumine		ERK1	ERK2			99.86%
Temuterkib		ERK1, IC₅₀: 5 nM	ERK2, IC₅₀: 5 nM			99.93%
Lidocaine	ERK					99.96%
Gamma-Linolenic acid		ERK1	ERK2			99.80%
Ravoxertinib		ERK1, IC₅₀: 6.1 nM	ERK2, IC₅₀: 3.1 nM			99.84%
Fucoxanthin			ERK2			99.38%
trans-Zeatin	ERK					99.77%
Apomorphine		ERK1	ERK2			99.48%
Lidocaine hydrochloride	ERK					99.84%
FR 180204		ERK1, Ki: 0.31 μM ERK1, IC₅₀: 0.51 μM	ERK2, Ki: 0.14 μM ERK2, IC₅₀: 0.33 μM			99.91%
ASN007		ERK1	ERK2			99.48%
Pachymic acid	ERK					99.94%
TERT activator-1		ERK1	ERK2			99.91%
LM22B-10	ERK					99.92%
6-OAU	ERK					99.77%
Anti-IL11 Antibody (X203)	ERK					98.53%
BIX02189				ERK5, IC₅₀: 59 nM		99.72%
XMD8-92				BMK1, Kd: 80 nM		99.48%
Peramivir		ERK1	ERK2			99.94%
Mianserin hydrochloride		ERK1	ERK2			99.95%
Peiminine		ERK1	ERK2			99.89%
Urocortin II, human		ERK1	ERK2			99.95%
MK-8353		ERK1, IC₅₀: 23 nM	ERK2, IC₅₀: 8.8 nM			98.13%
VX-11e			ERK2, Ki: 2 nM			98.94%
ERK1/2 inhibitor 1			ERK2, IC₅₀: 3.0 nM			99.58%
AX-15836				ERK5, IC₅₀: 8 nM		99.79%
Senkyunolide I		ERK1	ERK2			99.37%
ASTX029		ERK1	ERK2			99.86%
Lidocaine (Standard)	ERK
Pluripotin		ERK1, Kd: 98 nM				98.86%
Methylnissolin		ERK1	ERK2			99.92%
H-Ile-Lys-Val-Ala-Val-OH		ERK1	ERK2			99.35%
2"-O-Galloylhyperin		ERK1	ERK2			99.57%
Leucic acid		ERK1	ERK2			98.38%
4-Hydroxychalcone		ERK1	ERK2			99.29%
JWG-071				ERK5, IC₅₀: 88 nM		98.74%
Lidocaine hydrochloride hydrate	ERK					99.80%
AG126			ERK2			98.0%
Cafestol			ERK2			99.91%
CHPG	ERK					99.51%
Mogrol		ERK1	ERK2			99.76%
XMD17-109				ERK5, IC₅₀: 162 nM		99.14%
Broussonin E	ERK					98.11%
Ravoxertinib hydrochloride		ERK1, IC₅₀: 6.1 nM	ERK2, IC₅₀: 3.1 nM			99.44%
ERK5-IN-2				ERK5, IC₅₀: 0.82 μM ERK5 MEF2D, IC₅₀: 3 μM		98.45%
CHPG sodium salt	ERK					99.57%
Phellopterin	ERK					99.94%
Ganglioside GM1		ERK1	ERK2			99.0%
ERK5-IN-1				ERK5, IC₅₀: 87 nM		99.55%
CC-90003		ERK1	ERK2			99.50%
ASN007 benzenesulfonate		ERK1	ERK2			99.72%
Prostaglandin A2			ERK2			99.9%
Sanggenon C	ERK					98.46%
DEL-22379			ERK2, IC₅₀: 0.5 μM			99.69%
Paeonolide		ERK1	ERK2			99.58%
Geranial		ERK1	ERK2			99.51%
2,5-Dihydroxyacetophenone		ERK1	ERK2			99.95%
CKLF1-C27		ERK1	ERK2			98.02%
Corynoxeine		ERK1	ERK2			99.97%
Mianserin		ERK1	ERK2			99.42%
Gallic aldehyde		ERK1	ERK2			99.92%
MAP855	ERK, EC₅₀: 5 nM					98.48%
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside		ERK1	ERK2			98.92%
AT-533		ERK1	ERK2			98.38%
Myristicin	ERK					99.89%
HIOC	ERK					99.94%
CK2/ERK8-IN-1					ERK8, IC₅₀: 0.5 μM	99.0%
Loureirin B	ERK					99.96%
Longdaysin			ERK2, IC₅₀: 52 μM			99.83%
UNC1062		ERK1	ERK2			98.92%
Rineterkib		ERK1	ERK2			98.79%
KO-947		ERK1	ERK2			99.68%
Chondroitin sulfate (from chicken)		ERK1	ERK2			99.61%
N-(p-Coumaroyl) Serotonin		ERK1	ERK2			99.03%
Trimebutine		ERK1	ERK2			99.42%
Tizaterkib			ERK2, IC₅₀: 0.6 nM			99.09%
Magnolin		ERK1, IC₅₀: 87 nM	ERK2, IC₅₀: 16.5 nM			99.98%
β-Neo-Endorphin		ERK1	ERK2			98.97%
Trimebutine maleate		ERK1	ERK2			99.66%
4-Methylbenzylidene camphor		ERK1	ERK2			99.87%
Armepavine		ERK1	ERK2			99.53%
BAY885				ERK5, IC₅₀: 35 nM		99.33%
Fulipiftide			ERK2			99.38%
Methylthiouracil		ERK1	ERK2			98.0%
Deltonin		ERK1	ERK2			99.94%
Quin-C7		ERK1	ERK2			99.76%
Enniatin B1	ERK					99.34%
TCB-32 hydrochloride		ERK1	ERK2
Viridicatol	ERK					99.93%
BIX02188				ERK5, IC₅₀: 810 nM		98.05%
Ombuoside		ERK1	ERK2			99.68%
L-Citronellol	ERK					99.92%
Pheophytin a		ERK1	ERK2
Urocortin II, human acetate		ERK1	ERK2			99.61%
Ganglioside GT1b (bovine) ammonium		ERK1	ERK2			98.0%
ZINC12409120	ERK, IC₅₀: 5 μM					99.95%
Cearoin	ERK					99.09%
Cucurbitacin IIa		ERK1	ERK2			99.90%
SHR2415		ERK1, IC₅₀: 2.8 nM	ERK2, IC₅₀: 5.9 nM			98.04%
Alisol A 24-acetate	ERK					98.0%
SKLB-D18		ERK1, IC₅₀: 38.69 nM ERK1, Kd: 126.9 nM	ERK2, IC₅₀: 40.12 nM ERK2, Kd: 209.8 nM	ERK5, IC₅₀: 59.72 nM ERK5, Kd: 468.2 nM		98.06%
N-Feruloylserotonin		ERK1	ERK2			99.93%
ERK-IN-4			ERK2, Kd: 5 μM			98.30%
Hypothemycin		ERK1, Ki: 8.4 μM	ERK2, Ki: 2.4 μM			98.0%
[Tyr8] Bradykinin		ERK1	ERK2			99.61%
ML192		ERK1	ERK2			99.70%
Sugiol		ERK1	ERK2			99.88%
Cathepsin G		ERK1	ERK2
Hecogenin acetate		ERK1	ERK2			98.57%
Satratoxin H		ERK1	ERK2			99.7%
YK-8S	ERK
Wnt/β-catenin-IN-6	ERK					98.34%
ERK1/2 inhibitor 9		ERK1	ERK2
Isoprocurcumenol	ERK
EVT801	ERK, IC₅₀: 13 nM
KBU2046		ERK1	ERK2			99.52%
Pellitorine		ERK1	ERK2			99.84%
PPM-3				ERK5, IC₅₀: 62.4 ± 18. nM		98.2%
Vitisin A		ERK1	ERK2
ERK2-IN-4			ERK2, Ki: 0.006 μM			99.9%
ERK5-IN-5				ERK5		99.05%
Q-Peptide		ERK1	ERK2			99.46%
Benzanthrone		ERK1	ERK2
DCZ3301		ERK1	ERK2			99.73%
Sialorphin TFA		ERK1	ERK2
IL13Rα2 D1		ERK1	ERK2			99.17%
Alcudacigib		ERK1	ERK2
Peptide R54 acetate		ERK1	ERK2
SHY-867		ERK1	ERK2
PT-262	ERK					99.21%
Bohemine			ERK2, IC₅₀: 52 μM			98.93%
18:0-22:6 DG		ERK1	ERK2			99%
PROTAC HPK1 Degrader-5	ERK
AG01		ERK1	ERK2
ERK-CLIPTAC		ERK1	ERK2
TCB-32		ERK1	ERK2
Anti-inflammatory agent 35	ERK					99.77%
Enniatin B	ERK					99.86%
SHY-855		ERK1	ERK2
FGF7p	ERK					99.34%
β-Patchoulene		ERK1	ERK2
Antiproliferative agent-37		ERK1	ERK2			98.29%
FTI-277		ERK1	ERK2
RNK08954		ERK1	ERK2
ERK2 IN-1			ERK2, IC₅₀: 7 nM
ERK-IN-2			ERK2, IC₅₀: 1.8 nM
Anti-inflammatory agent 99	ERK
Autotaxin-IN-8		ERK1	ERK2
Cm-CATH2	ERK
ERK5 ligand-1				ERK5
MK-8353 hydrochloride		ERK1, IC₅₀: 23 nM	ERK2, IC₅₀: 8.8 nM
ERK5-IN-3				ERK5, IC₅₀: 6 ± 1 nM
α4β1 antagonist-1		ERK1	ERK2
Aloisine A		ERK1, IC₅₀: 18 μM	ERK2, IC₅₀: 22 μM
Deltafluorine		ERK1	ERK2
G721-0282	ERK					99.96%
Ravoxertinib (GMP)		ERK1	ERK2
EGFR-IN-189		ERK1	ERK2
JWG-045				ERK5
ERK-IN-7		ERK1, IC₅₀: 5 nM	ERK2, IC₅₀: 7 nM
EGFR-IN-197	ERK
ERK1/2 inhibitor 13		ERK1, IC₅₀: 91.71 nM	ERK2, IC₅₀: 97.87 nM
NY0123		ERK1	ERK2
LQEQ-19 (mouse, rat)		ERK1	ERK2
Cot-IN-4	ERK
ERK-IN-2 free base			ERK2, IC₅₀: 1.8 nM
BAY-693				ERK5, IC₅₀: 6.4 μM
Apoptosis inducer 55		ERK1	ERK2
DCZ19931		ERK1	ERK2
ERK-IN-8			ERK2, IC₅₀: ≤50 nM
MHJ-627				ERK5
NLX-219		ERK1	ERK2
ERK2 IN-5			ERK2, Ki: 86 nM
INH2BP		ERK1	ERK2
STK899704	ERK
AHL-7160		ERK1	ERK2
SF-3-030		ERK1	ERK2
Norkurarinol		ERK1	ERK2
Desipramine		ERK1	ERK2
EGFR-IN-182	ERK
ERK2 allosteric-IN-1			ERK2, IC₅₀: 11 μM
Anticancer agent 301		ERK1	ERK2
OP-1118		ERK1	ERK2
PDGFRA/CAIX/XII-IN-1		ERK1	ERK2
GIT1-IN-1		ERK1	ERK2
PARP1/ERK IN-1			ERK2, IC₅₀: 1.8 nM
EGFR-IN-201		ERK1, : 0.705 μg/mL
CKLF1-C27 TFA		ERK1	ERK2
Enniatin A1	ERK
PROTAC RET Degrader 2	ERK
Isostrictiniin		ERK1	ERK2
NS-417 free base		ERK1	ERK2
Sonvuterkib		ERK1, IC₅₀: 1.4 nM	ERK2, IC₅₀: 0.54 nM
24-O-Acetyllycoclavanol		ERK1	ERK2
Urocortin II, human TFA		ERK1	ERK2
LHQ766		ERK1	ERK2
NEPP11		ERK1	ERK2
Anti-inflammatory agent 31		ERK1	ERK2
Evariquinone		ERK1	ERK2
KRAS G12C-IN-78		ERK1	ERK2
ERK1/2 inhibitor 10		ERK1, IC₅₀: 0.11 nM	ERK2, IC₅₀: 0.8 nM
Myristoyl-MEK1 Derived Peptide Inhibitor 1	ERK, IC₅₀: 13 μM (The in vivo inhibitory potency is determined in both PMA-treated NIH 3T3 cells and NGF-stimulated PC12 cells.)		ERK2, IC₅₀: 10 μM (The in vitro inhibitory potency of the peptides is measured based on their ability to inhibit MEK1-mediated phosphorylation of ERK2. )
CXJ-2	ERK
KRASG12C IN-19	ERK, IC₅₀: 24.6 nM
PCC0105005	ERK
ERK5-IN-7				ERK5, IC₅₀: 403.4 nM
ERK2-IN-6			ERK2, IC₅₀: 7.9 nM
Hydrostatin-TL1	ERK
Breceptin		ERK1	ERK2
Trimebutine-d₃ hydrochloride		ERK1	ERK2
SHP1-IN-2		ERK1	ERK2
C11 peptide-1		ERK1	ERK2
MK2-IN-5		ERK1	ERK2
Cudraflavone B	ERK
Sitagliptin hydrochloride		ERK1	ERK2
EUK-189		ERK1	ERK2
ERK5-IN-4				ERK5
Len-604		ERK1	ERK2
FLC-8	ERK
Trimebutine-d₅ fumarate		ERK1	ERK2
Anticancer agent 231		ERK1	ERK2
ERK5-IN-6	ERK
Trimebutine maleate (Standard)		ERK1	ERK2
(3S)-Tanzisertib hydrochloride		ERK1, IC₅₀: 0.48 μM
Phenylhydroquinone		ERK1	ERK2			99.21%
N-(p-Coumaroyl) Serotonin (Standard)		ERK1	ERK2
Tizaterkib hexanedioic acid			ERK2, IC₅₀: 0.6 nM
Methyl helicterate		ERK1	ERK2
Trimebutine (Standard)		ERK1	ERK2
MptpB-IN-3		ERK1	ERK2
Berkeleyacetal C		ERK1	ERK2
Cavidine		ERK1	ERK2
2"-O-Galloylhyperin (Standard)		ERK1	ERK2

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