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Progesterone  (Synonyms: Pregn-4-ene-3,20-dione)

Cat. No.: HY-N0437 Purity: 99.42%
COA Handling Instructions

Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

For research use only. We do not sell to patients.

Progesterone Chemical Structure

Progesterone Chemical Structure

CAS No. : 57-83-0

Size Price Stock Quantity
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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 73 In-stock
Solution
10 mM * 1 mL in DMSO USD 73 In-stock
Solid
100 mg USD 66 In-stock
1 g USD 79 In-stock
5 g USD 106 In-stock
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Customer Review

Based on 15 publication(s) in Google Scholar

Other Forms of Progesterone:

Top Publications Citing Use of Products
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Description

Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Progesterone (Injections; 1 mg; three consecutive daily) stimulates vessel maturation in the mouse endometrium[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult female mice (7-13 wk, 18-28 g)[4]
Dosage: 1 mg
Administration: Injections; three consecutive daily
Result: Stimulated vessel maturation in the mouse endometrium.
Clinical Trial
Molecular Weight

314.46

Formula

C21H30O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC([C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (159.00 mM; ultrasonic and warming and heat to 60°C)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1801 mL 15.9003 mL 31.8005 mL
5 mM 0.6360 mL 3.1801 mL 6.3601 mL
10 mM 0.3180 mL 1.5900 mL 3.1801 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  50% PEG300    50% Saline

    Solubility: 20 mg/mL (63.60 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.08 mg/mL (6.61 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.08 mg/mL (6.61 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.08 mg/mL (6.61 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: 99.42%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Progesterone
Cat. No.:
HY-N0437
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