Nonsteroidal progesterone receptor antagonists based on 6-thiophenehydroquinolines
- Bioorg Med Chem Lett. 2000 Mar 6;10(5):415-8. doi: 10.1016/s0960-894x(00)00011-1.
Affiliations
- 1. Ligand Pharmaceuticals, San Diego, CA 92121, USA. [email protected]
PMID: 10743938
DOI: 10.1016/s0960-894x(00)00011-1
Abstract
Synthesis and biological evaluation of 6-thiophene 1,2-dihydro or 1,2,3,4-tetrahydroquinoline derivatives resulted in a number of potent nonsteroidal antiprogestins.