57-83-0
Chemical Structure
Progesterone
Synonym(s): Pregn-4-ene-3,20-dione
- CAS No.: 57-83-0
- Formula:C21H30O2
- Molecular Weight:314.46
IUPAC Name: (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: RJKFOVLPORLFTN-LEKSSAKUSA-N
SMILES: CC([C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O
Biological Activity: Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Progesterone | 99.79% | Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | ||||||||||||||||||||
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Progesterone (Standard) | 99.20% | Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | ||||||||||||||||||||
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Progesterone-d9 | 99.93% | Progesterone-d9 is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | ||||||||||||||||||||
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Progesterone-13C3 | 99.60% | Progesterone-13C3 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | ||||||||||||||||||||
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Progesterone-13C5 | Progesterone-13C5 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | |||||||||||||||||||||
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Progesterone-13C2 | 99.7% | Progesterone-13C2 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | ||||||||||||||||||||
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Progesterone carboxylic acid (Standard) | ≥98% | Progesterone carboxylic acid (Standard) is the analytical standard of Progesterone carboxylic acid (HY-108409). This product is intended for research and analytical applications. Progesterone carboxylic acid (Testosterone-17β-carboxylic acid) is an androstenedione analogue. Progesterone carboxylic acid can conjugate with 20-mer peptide nucleic acid (PNA) and the conjugate has superior binding capacity on complementary DNA. Progesterone carboxylic acid can be used for cancers and type 2 diabetes (T2D) research. | ||||||||||||||||||||
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Aldosterone-d8 | 99.2% | Aldosterone-d8 is a deuterium labeled Aldosterone. Aldosterone, produced in the adrenal zona glomerulosa, regulates blood pressure. | ||||||||||||||||||||
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Cholestenone-d5 | 98.04% | Cholestenone-d5 is the deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells. | ||||||||||||||||||||
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21-Deoxycortisol-d8 | 98.79% | 21-Deoxycortisol-d8 is the d8-labeled 21-Deoxycortisol (HY-113405). 21-Deoxycortisol is an adrenal-specific C21 steroid that accumulates via alternative pathways due to 21-hydroxylase (CYP21A2/P450c21) deficiency. 21-Deoxycortisol serves as a sensitive and specific biomarker for steroid 21-hydroxylase deficiency (21OHD). | ||||||||||||||||||||
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Deoxycorticosterone (Standard) | 99.83% | Deoxycorticosterone (Standard) is the analytical standard of Deoxycorticosterone. This product is intended for research and analytical applications. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. | ||||||||||||||||||||
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Deoxycorticosterone-d8 | 97.77% | Deoxycorticosterone-d8 is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. | ||||||||||||||||||||
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11-Beta-hydroxyandrostenedione-d7 | 97.0% | 11-Beta-hydroxyandrostenedione-d7 is the deuterium labeled 11-Beta-hydroxyandrostenedione. 11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor | ||||||||||||||||||||
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Org OD 02-0 | 99.7% | Org OD 02-0 (10-Ethenyl-19-norprogesterone) is a selective mPRα/PAQR7 agonist that can cross the blood-brain barrier. Org OD 02-0 targets mPRα with an IC50 of 33.9 nM and activates the PI3K-AKT, MAPK/ERK, and Src signaling pathways. Org OD 02-0 upregulates SERCA2, phosphorylates phospholamban, increases sarcoplasmic reticulum calcium uptake, decreases RhoA/ROCK activity, and induces vascular smooth muscle relaxation and nitric oxide production. Org OD 02-0 can be used for research on Parkinson's disease, glioblastoma, apnea, and hypertension. | ||||||||||||||||||||
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EIDD-036 | EIDD-036, is the blood-brain barrier penetrant C-20 oxime of Progesterone (HY-N0437), that binds progesterone receptor (PR) with an IC50 of 171 nM. EIDD-036 is the active metabolite of EIDD-1723 (HY-125547). EIDD-036 exhibits promising challenges for rapid administration in acute trauma. EIDD-036 can be used for the study of traumatic brain injury (TBI). | |||||||||||||||||||||
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Cortodoxone-d5 | 99.90% | Cortodoxone-d5 is the deuterium labeled Cortodoxone. | ||||||||||||||||||||
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Norgestrel-d6 | 99.53% | Norgestrel-d6 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Norgestrel-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Norethindrone-d6 | 99.88% | Norethindrone-d6 is the deuterium labeled Norethindrone. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea. Norethindrone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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17α-Hydroxyprogesterone-d8 | 98.52% | 17α-Hydroxyprogesterone-d8 is the deuterium labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens. | ||||||||||||||||||||
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Corticosterone-d8 | 99.91% | Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. | ||||||||||||||||||||
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Progesterone impurity 5 | Progesterone impurity 5 is an impurity of Progesterone. | |||||||||||||||||||||
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Progesterone impurity 2 | Progesterone impurity 2 is an impurity of Progesterone. | |||||||||||||||||||||
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Progesterone impurity 8 | Progesterone impurity 8 (Isoprogesterone) is an impurity of Progesterone. | |||||||||||||||||||||
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