Heat-Clearing and Detoxification Traditional Chinese Medicine Compound Library

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Based on 83 publication(s) in Google Scholar

Heat-clearing and detoxification is a specific treatment method in the research of traditional Chinese medicine (TCM), which is clinically used to treat infectious diseases with remarkable effect. Over the past decades, the research of heat-clearing and detoxification treatment has been one of the most active fields of combining traditional Chinese and western medicines, and has made remarkable achievements. Nowadays, the application field of heat-clearing and detoxification traditional Chinese medicine is not only limited to antibacterial and antiviral, but also has made progress in the research fields of anti-inflammatory reaction, anti-endotoxin, anti-peroxidative damage, anti-inflammatory cytokines, enhancement of immune function, protection of cellular organelles, and maintenance of calcium homeostasis. In addition to this, clearing heat and removing toxins has also made significant research progress in non-infectious diseases, for example, in tumors, cardiovascular diseases, renal diseases, blood diseases, geriatrics, and diabetes, all of which have shown good curative effect.

MCE can supply 1,282 monomer component from more than a hundred sources of heat-clearing and detoxification TCM, which can be used in TCM studies, drug development and mechanism-based studies.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Service

Description & Advantages

•   A unique collection of 1,282 heat-clearing and detoxification traditional Chinese medicine for high-throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of compounds for diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 1,282 heat-clearing and detoxification traditional Chinese medicine supplied as pre-dissolved Solutions or Solid.

Solution: 1,236 compounds supplied in 10 mM solution, 41 compounds supplied in 2 mM solution, 5 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage
-80°C
Shipping
Blue ice or dry ice

Documentation

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Composition

Apoptosis (306)

Bacterial (171)

NF-κB (152)

Autophagy (131)

Fungal (70)

p38 MAPK (68)

Parasite (66)

COX (63)

Akt (62)

PI3K (47)

Keap1-Nrf2 (42)

ERK (40)

Caspase (39)

JNK (35)

STAT (30)

PPAR (28)

AMPK (24)

mTOR (24)

MMP (22)

HIV (20)

Tyrosinase (20)

Antibiotic (19)

Amyloid-β (17)

PKC (15)

SOD (14)

HSV (12)

JAK (12)

SARS-CoV (11)

PERK (10)

CDK (9)

EGFR (9)

Mitophagy (9)

nAChR (9)

Wnt (9)

HBV (8)

mAChR (8)

PARP (8)

HSP (7)

MDM-2/p53 (7)

Sirtuin (7)

VEGFR (7)

CXCR (6)

FGFR (6)

MEK (6)

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200 mg
USD 120
In-stock
Estimated to ship on August 31 More
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
Estimated to ship on August 31 More