2. Peptides
  3. IRS1-derived peptide

IRS1-derived peptide is a biological active peptide. (This is a peptide fragment (979-989) of the insulin receptor substrate-1 containing the sequence motif YMXM known to bind to the two domains of SH2 on the 85kDa subunit of phosphoinositide 3-kinase.)

For research use only. We do not sell to patients.

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IRS1-derived peptide Chemical Structure

IRS1-derived peptide Chemical Structure

CAS No. : 865778-50-3

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1 mg USD 80 In-stock
5 mg USD 200 In-stock
10 mg USD 300 In-stock
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Based on 1 publication(s) in Google Scholar

IRS1-derived peptide Related Antibodies

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Description

IRS1-derived peptide is a biological active peptide. (This is a peptide fragment (979-989) of the insulin receptor substrate-1 containing the sequence motif YMXM known to bind to the two domains of SH2 on the 85kDa subunit of phosphoinositide 3-kinase.)

Molecular Weight

1513.78

Formula

C63H108N20O19S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Met-Gln-Ile-Gly-NH2
Sequence Shortening

KKSRGDYMTMQIG-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (66.06 mM; Need ultrasonic)

DMSO : 25 mg/mL (16.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6606 mL 3.3030 mL 6.6060 mL
5 mM 0.1321 mL 0.6606 mL 1.3212 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 0.6606 mL 3.3030 mL 6.6060 mL 16.5149 mL
5 mM 0.1321 mL 0.6606 mL 1.3212 mL 3.3030 mL
10 mM 0.0661 mL 0.3303 mL 0.6606 mL 1.6515 mL
15 mM 0.0440 mL 0.2202 mL 0.4404 mL 1.1010 mL
H2O 20 mM 0.0330 mL 0.1651 mL 0.3303 mL 0.8257 mL
25 mM 0.0264 mL 0.1321 mL 0.2642 mL 0.6606 mL
30 mM 0.0220 mL 0.1101 mL 0.2202 mL 0.5505 mL
40 mM 0.0165 mL 0.0826 mL 0.1651 mL 0.4129 mL
50 mM 0.0132 mL 0.0661 mL 0.1321 mL 0.3303 mL
60 mM 0.0110 mL 0.0550 mL 0.1101 mL 0.2752 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IRS1-derived peptide865778-50-3OthersInhibitorinhibitorinhibit

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