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Aclimostat (Synonyms: ZGN-1061)

Cat. No.: HY-114196
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Aclimostat (ZGN-1061) is a potent inhibitor of the MetAP2 enzyme and displays favorable efficacy and safety in preclinical studies. ZGN-1061 produced similar efficacy as beloranib for weight loss, improvements in metabolic parameters in a mouse model of obesity and insulin resistance, and concordant changes in gene transcription in HepG2 cells.

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Aclimostat Chemical Structure

Aclimostat Chemical Structure

CAS No. : 2082752-83-6

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Description

Aclimostat (ZGN-1061) is a potent inhibitor of the MetAP2 enzyme and displays favorable efficacy and safety in preclinical studies. ZGN-1061 produced similar efficacy as beloranib for weight loss, improvements in metabolic parameters in a mouse model of obesity and insulin resistance, and concordant changes in gene transcription in HepG2 cells[1].

Molecular Weight

478.62

Formula

C₂₆H₄₂N₂O₆

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Aclimostat
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HY-114196
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