1. Natural Products
  2. Flavonoids

Flavonoids

Flavonoids (or bioflavonoids) are a class of plant and fungus secondary metabolites. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and heterocyclic ring (C). This carbon structure can be abbreviated C6-C3-C6. They can be classified into: flavonoids or bioflavonoids, isoflavonoids, neoflavonoids. Flavonoids are widely distributed in plants, fulfilling many functions. Flavonoids are the most important plant pigments for flower coloration, producing yellow or red/blue pigmentation in petals designed to attract pollinator animals. In higher plants, flavonoids are involved in UV filtration, symbiotic nitrogen fixation and floral pigmentation. They may also act as chemical messengers, physiological regulators, and cell cycle inhibitors. In addition, some flavonoids have inhibitory activity against organisms that cause plant diseases.

Flavonoids (116):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-14596
    Genistein 446-72-0 99.64%
    Genistein is a potent inhibitor of the protein tyrosine kinase (PTK) activity of the EGFR in vitro with an IC50 of 0.7 μg/mL (0.6 μM).
    Genistein
  • HY-18085
    Quercetin 117-39-5 98.21%
    Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4±0.6 μM, 3.0±0.0 μM and 5.4±0.3 μM for PI3K γ, PI3K δ and PI3K β, respectively.
    Quercetin
  • HY-13653
    (-)-Epigallocatechin Gallate 989-51-5 99.60%
    (-)-Epigallocatechin Gallate is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase, and blocks the activation of EGF receptors and HER-2 receptors.
    (-)-Epigallocatechin Gallate
  • HY-14590
    Kaempferol 520-18-3 99.47%
    Kaempferol inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK.
    Kaempferol
  • HY-N0155
    Nobiletin 478-01-3 99.96%
    Nobiletin, a natural polymethoxylated flavone, is identified as a clock amplitude-enhancing small molecule.
    Nobiletin
  • HY-N0018
    Daidzin 552-66-9 99.04%
    Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone.
    Daidzin
  • HY-N1201
    Apigenin 520-36-5 >98.0%
    Apigenin is a non-toxic and non-mutagenic flavone that exists abundantly in numerous herbs and vegetables.
    Apigenin
  • HY-N0102
    Isoliquiritigenin 961-29-5
    Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza glabra, which inhibits aldose reductase with an IC50 of 320 nM.
    Isoliquiritigenin
  • HY-N0019
    Daidzein 486-66-8 99.69%
    Daidzein is a soy isoflavone, which acts as a PPAR activator.
    Daidzein
  • HY-N0143
    Phlorizin 60-81-1
    Phlorizin, a natural product and dietary constituent found in a number of fruit trees, is a 2'-glucoside of phloretin, Phlorizin is a competitive and classic inhibitor of hSGLT1(Ki=300 nM) and hSGLT2(Ki= 39 nM).
    Phlorizin
  • HY-13748
    Silibinin 22888-70-6 >98.0%
    Silibinin, an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.
    Silibinin
  • HY-N0796
    Procyanidin B2 29106-49-8 99.36%
    Procyanidin B2 exerts a potent and beneficial role in reducing granulosa cell apoptosis and inducing autophagy process,and exerts a variety of potent protective pharmacological effects on diabetic complications.
    Procyanidin B2
  • HY-N0197
    Baicalin 21967-41-9 98.01%
    Baicalin, one the effective compositions of scutellaria baicalensis, possesses multiple properities such as antioxidant, anti-tumor, anti-HIV, treating cardiovascular disease and so on.
    Baicalin
  • HY-N0162
    Luteolin 491-70-3
    Luteolin is a falconoid compound, which exhibits anticancer properties.
    Luteolin
  • HY-N0400
    Wogonin 632-85-9 99.82%
    Wogonin is a naturally occurring mono-flavonoid, can inhibit the activity of CDK8 and Wnt, and exhibits anti-inflammatory and anti-tumor effects.
    Wogonin
  • HY-N0014
    Icariin 489-32-7 >98.0%
    Icariin(Ieariline) is a major constituent of flavonoids from the Chinese medicinal herb Epimedium brevicornum; exhibits multiple biological properties, including anti-inflammatory, neuroregulatory and neuroprotective activities.
    Icariin
  • HY-N0148
    Rutin 153-18-4 98.67%
    Rutin, a naturally occurring flavonoid glycoside, has antioxidant, anti-inflammatory, anti-allergic, anti-angiogenic and antiviral properties.
    Rutin
  • HY-N0372
    Licochalcone A 58749-22-7 99.44%
    Licochalcone A, a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch, presents obvious anti-cancer effects.
    Licochalcone A
  • HY-N0133
    Tangeretin 481-53-8 98.98%
    Tangeretin, a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and was also selected as a Notch-1 inhibitor.
    Tangeretin
  • HY-15097
    Myricetin 529-44-2 99.41%
    Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities.
    Myricetin