1. Natural Products
  2. Flavonoids

Flavonoids

Flavonoids (or bioflavonoids) are a class of plant and fungus secondary metabolites. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and heterocyclic ring (C). This carbon structure can be abbreviated C6-C3-C6. They can be classified into: flavonoids or bioflavonoids, isoflavonoids, neoflavonoids. Flavonoids are widely distributed in plants, fulfilling many functions. Flavonoids are the most important plant pigments for flower coloration, producing yellow or red/blue pigmentation in petals designed to attract pollinator animals. In higher plants, flavonoids are involved in UV filtration, symbiotic nitrogen fixation and floral pigmentation. They may also act as chemical messengers, physiological regulators, and cell cycle inhibitors. In addition, some flavonoids have inhibitory activity against organisms that cause plant diseases.

Flavonoids (144):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-18085
    Quercetin 117-39-5 >98.0%
    Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4±0.6 μM, 3.0±0.0 μM and 5.4±0.3 μM for PI3K γ, PI3K δ and PI3K β, respectively.
    Quercetin
  • HY-14596
    Genistein 446-72-0 99.64%
    Genistein, a soy isoflavone, is a multiple tyrosine kinases inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
    Genistein
  • HY-13653
    (-)-Epigallocatechin Gallate 989-51-5 99.60%
    (-)-Epigallocatechin Gallate is an antioxidant polyphenol flavonoid form green tea, and inhibits the activation of EGFR, HER2 and HER3, with antitumor activity.
    (-)-Epigallocatechin Gallate
  • HY-N1201
    Apigenin 520-36-5 >98.0%
    Apigenin is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
    Apigenin
  • HY-N0796
    Procyanidin B2 29106-49-8 99.36%
    Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.
    Procyanidin B2
  • HY-N0155
    Nobiletin 478-01-3 99.96%
    Nobiletin, a natural polymethoxylated flavone, is identified as a clock amplitude-enhancing small molecule.
    Nobiletin
  • HY-N0197
    Baicalin 21967-41-9 98.01%
    Baicalin is a flavonoid glycoside isolated from Scutellaria baicalensis. Baicalin reduces the expression of NF-κB.
    Baicalin
  • HY-14590
    Kaempferol 520-18-3 99.47%
    Kaempferol inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK.
    Kaempferol
  • HY-N0102
    Isoliquiritigenin 961-29-5 98.24%
    Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza glabra, which inhibits aldose reductase with an IC50 of 320 nM.
    Isoliquiritigenin
  • HY-N0162
    Luteolin 491-70-3 98.14%
    Luteolin is a falconoid compound, which exhibits anticancer properties.
    Luteolin
  • HY-N0014
    Icariin 489-32-7 >98.0%
    Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator.
    Icariin
  • HY-N0143
    Phlorizin 60-81-1
    Phlorizin is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.
    Phlorizin
  • HY-N0019
    Daidzein 486-66-8 99.66%
    Daidzein is a soy isoflavone, which acts as a PPAR activator.
    Daidzein
  • HY-N0018
    Daidzin 552-66-9 99.04%
    Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone.
    Daidzin
  • HY-15097
    Myricetin 529-44-2 99.41%
    Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities.
    Myricetin
  • HY-N0182
    Fisetin 528-48-3 >98.0%
    Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects.
    Fisetin
  • HY-13748
    Silibinin 22888-70-6 >98.0%
    Silibinin, an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.
    Silibinin
  • HY-N0196
    Baicalein 491-67-8 >98.0%
    Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 mM.
    Baicalein
  • HY-N1067
    Xanthohumol 6754-58-1 99.68%
    Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities.
    Xanthohumol
  • HY-N0751
    Scutellarin 27740-01-8 >98.0%
    Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts.
    Scutellarin