2. Natural Products
  3. Flavonoids
  4. Isoflavanones

Isoflavanones

Isoflavanones (28):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-13425
    Deguelin 522-17-8 99.20%
    Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
    Deguelin
  • HY-N1461
    Dihydrodaidzein 17238-05-0 99.38%
    Dihydrodaidzein is one of the most prominent dietary phytoestrogens.
    Dihydrodaidzein
  • HY-N4202
    Dihydrorotenone 6659-45-6 99.66%
    Dihydrorotenone is an insecticide and irreversible inhibitor of mitochondrial complex I. Dihydrorotenone may induce Parkinson's disease. Dihydrorotenone induces apoptosis in human plasma cells by triggering endoplasmic reticulum stress and activating the p38 signaling pathway. The oral LD50 of dihydrorotenone in rats is approximately 2.5 g/kg. Dihydrorotenone exhibits insecticide activity and cytotoxicity to plasma cells. Dihydrorotenone can be used to establish animal models of Parkinson's disease, safety assessment of natural pesticides, and potential cancer chemoprevention studies.
    Dihydrorotenone
  • HY-N5116
    Neoisoastilbin 54141-72-9 99.93%
    Neoisoastilbin possesses antioxidant, anti-hyperuricemic and anti-Inflammatory activities.
    Neoisoastilbin
  • HY-N3479
    Isohemiphloin 3682-02-8 98.31%
    Isohemiphloin is a flavonoid compound.
    Isohemiphloin
  • HY-N19816
    7-O-Methyl glabranin 75291-75-7
    7-O-Methyl glabranin is a flavonoid compound and also an inhibitor of LPS-induced TNF-α and IL-1β production. 7-O-Methyl glabranin can be used in the research of diseases such as inflammation.
    7-O-Methyl glabranin
  • HY-N19426
    Tetrapterol A 160098-94-2
    Tetrapterol A is an isoflavanone compound. Tetrapterol A can be isolated from the roots of Sophora tetraptera.
    Tetrapterol A
  • HY-N4076
    Dihydrogenistein 21554-71-2
    Dihydrogenistein is a reductive metabolite of Calycosin (HY-N0519), is an active metabolic intermediate.
    Dihydrogenistein
  • HY-N6059
    Ophiopogonanone A 75239-63-3 99.24%
    Ophiopogonanone A is a homoisoflavonoidal compound isolated as a constitutent of Ophiopogonis tuber.
    Ophiopogonanone A
  • HY-N1166
    Tephrosin 76-80-2 98.02%
    Tephrosin is a natural rotenoid which has potent antitumor activities. Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors.
    Tephrosin
  • HY-N7372
    Licoisoflavanone 66067-26-3
    Licoisoflavanone is an orally active isoflavane-based immunomodulator with multiple activities including antiviral, anti-inflammatory, cytoprotective and cancer cell apoptosis-inducing effects. Licoisoflavanone can be isolated from the roots and rhizomes of Glycyrrhiza uralensis Fisch. Licoisoflavanone not only enhances the body's immunity, but also effectively prevents acute respiratory distress syndrome and multiple organ damage by alleviating cytokine storm, thereby reducing the degree of inflammation. In rats, Licoisoflavanone undergoes multiple metabolic transformation processes such as glucuronidation, hydroxylation, sulfation, methylation and dehydrogenation. Licoisoflavanone has become an important candidate molecule for research on COVID-19 and related inflammatory diseases.
    Licoisoflavanone
  • HY-N4200
    S-Dihydrodaidzein 879559-75-8
    S-Dihydrodaidzein is the (S)-enantiomer of dihydrodaidzein which is one of the most prominent dietary phytoestrogens.
    S-Dihydrodaidzein
  • HY-123351
    Kievitone 40105-60-0 99.67%
    Kievitone, an isoflavanone, could be isolated from hypocotyls of Phaseolus vulgaris L. infected with Rhizoctonia solani Kühn. Kievitone has antifungal activity and antitumor activity.
    Kievitone
  • HY-N2422
    7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside 94367-43-8 99.80%
    7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside is a bioactive isoflavonoid isolated from Radix Astragali (Huangqi).
    7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside
  • HY-N6250
    Isomucronulatol 7-O-glucoside 136087-29-1 99.40%
    Isomucronulatol 7-O-glucoside (Isomucronulatol 7-O-β-D-glucoside) is an isoflavonoid glycoside isolated from the roots of Astragalus membranaceus. Isomucronulatol 7-O-glucoside targets inflammation-related pathways in vitro to exert anti-inflammatory activity without cytotoxicity at effective concentrations. Isomucucronulatol 7-O-glucoside inhibits NO production and weakly suppresses IL‑12 p40 production in vitro. Isomucronulatol 7-O-glucoside can be used for the research on inflammation.
    Isomucronulatol 7-O-glucoside
  • HY-13425R
    Deguelin (Standard) 522-17-8
    Deguelin (Standard) is the analytical standard of Deguelin. This product is intended for research and analytical applications. Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
    Deguelin (Standard)
  • HY-N16503
    8-Methyldisporopsin 1671098-51-3
    8-Methyldisporopsin (Compound 7) is a C-methylated homoisoflavanone. 8-Methyldisporopsin can be isolated from rhizomes of Polygonatum cyrtonema.
    8-Methyldisporopsin
  • HY-N16530
    8-Methyl-2'-deoxydisporopsin 1671098-52-4
    8-Methyl-2'-deoxydisporopsin (Compound 2) is a C-methylated high isomeric ketone and is one of the characteristic secondary metabolites of the Liliaceae family. 8-Methyl-2'-deoxydisporopsin shows no cytotoxic activity.
    8-Methyl-2'-deoxydisporopsin
  • HY-N10085
    Parvisoflavanone 49776-79-6
    Parvisoflavanone is an isoflavanone that can be isolated from Mucuna pruriens.
    Parvisoflavanone
  • HY-N11533
    6-Formyl-isoophiopogonanone B 88700-30-5
    6-Formyl-isoophiopogonanone B is a homoisoflavonoid, which can be isolated from Ophiopogon japonicus.
    6-Formyl-isoophiopogonanone B