1. Neuronal Signaling
    Autophagy
  2. Amyloid-β
    Autophagy
  3. Rutin

Rutin (Synonyms: Rutoside; Quercetin 3-O-rutinoside)

Cat. No.: HY-N0148 Purity: >98.0%
Handling Instructions

Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress.

For research use only. We do not sell to patients.

Rutin Chemical Structure

Rutin Chemical Structure

CAS No. : 153-18-4

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10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
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5 g USD 60 In-stock
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10 g USD 84 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress[1][2][3].

In Vivo

Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signaling[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

610.52

Formula

C₂₇H₃₀O₁₆

CAS No.

153-18-4

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 35 mg/mL (57.33 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6379 mL 8.1897 mL 16.3795 mL
5 mM 0.3276 mL 1.6379 mL 3.2759 mL
10 mM 0.1638 mL 0.8190 mL 1.6379 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

RutinRutoside Quercetin 3-O-rutinosideAmyloid-βAutophagyβ-amyloid peptideAbetaflavonoidanti-inflammatoryantidiabeticantioxidantneuroprotectivenephroprotectivehepatoprotectivebloodbrainbarrierInhibitorinhibitorinhibit

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Rutin
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