Dimethyl L-glutamate
Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the KATP channel activities. Dimethyl L-glutamate inhibits E. gracilis growth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism.
For research use only. We do not sell to patients.
- CAS No.: 6525-53-7
- Formula: C7H13NO4
- Molecular Weight:175.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
KATP channel[4]
Chemical Information
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CAS No. 6525-53-7
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Molecular Weight 175.18
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Formula C7H13NO4
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Synonyms
Dimethyl glutamate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. J Cancelas, et al. Potentiation by glutamic acid dimethyl ester of GLP-1 insulinotropic action in fed anaesthetized rats. Int J Mol Med. 2001 Nov;8(5):531-2. [Content Brief]
[3]. I S Owens, et al. Induction of abnormal cell division in Euglena gracilis by glutamic diethyl ester. J Protozool. 1969 May;16(2):211-5. [Content Brief]
[4]. Hidenori Katsuta, et al. Insulinotropic action of glutamate is dependent on the inhibition of ATP-sensitive potassium channel activities in MIN 6 beta cells. Biochem Biophys Res Commun. 2003 Nov 21;311(3):660-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)