1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
    Neuronal Signaling
  3. iGluR
  4. NMDA Receptor Isoform

NMDA Receptor

 

NMDA Receptor Related Products (61):

Cat. No. Product Name Effect Purity
  • HY-17551
    NMDA
    Agonist ≥98.0%
    NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.
  • HY-100806
    Kynurenic acid
    Antagonist 99.58%
    Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor.
  • HY-Y0966
    Glycine
    99.26%
    Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
  • HY-N0215
    L-Phenylalanine
    Antagonist 99.96%
    L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli.
  • HY-B0030
    D-Cycloserine
    Agonist 99.91%
    D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes.
  • HY-147260
    Dalzanemdor
    Modulator
    Dalzanemdor (SAGE-718) is a N-methyl-D-aspartate (NMDA) receptor positive allosteric modulator.
  • HY-147352
    NMDA receptor potentiator-1
    Modulator
    NMDA receptor potentiator-1 (Compound 1368) is a subunit selective NMDA receptor potentiator with IC50s of 4 μM and 5 μM against NR2C and NR2D expression, respectively.
  • HY-100667
    UBP608
    Modulator
    UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator.
  • HY-P0117A
    Tat-NR2B9c TFA
    Inhibitor 99.67%
    Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively.
  • HY-N2072
    Transcrocetin
    Antagonist 98.04%
    Transcrocetin (trans-Crocetin), extracted from saffron (Crocus sativus L.
  • HY-17387
    (-)-Huperzine A
    Antagonist ≥98.0%
    (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity.
  • HY-12294A
    PEAQX tetrasodium hydrate
    Antagonist ≥98.0%
    PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B, respectively.
  • HY-N2370
    24-Hydroxycholesterol
    Activator ≥99.0%
    24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR.
  • HY-100808
    D-Serine
    Agonist ≥98.0%
    D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor.
  • HY-107512
    Kynurenic acid sodium
    Antagonist 99.76%
    Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor.
  • HY-N0368
    Linalool
    Inhibitor ≥98.0%
    Linalool is natural monoterpene in essential olis of coriander, acts as a competitive antagonist of Nmethyl d-aspartate (NMDA) receptor, with anti-tumor, anti-cardiotoxicity activity.
  • HY-P1594A
    Dynorphin A (1-10) (TFA)
    Inhibitor 99.43%
    Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor.
  • HY-B1270
    Isoxsuprine hydrochloride
    Antagonist 99.87%
    Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively.
  • HY-42068
    (-)-Aspartic acid
    Agonist ≥98.0%
    (-)-Aspartic acid is an endogenous NMDA receptor agonist.
  • HY-B0369A
    Orphenadrine citrate
    Antagonist 99.95%
    Orphenadrine citrate is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a Ki of 6.0 μM.