1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
    Neuronal Signaling
  3. iGluR
  4. NMDA Receptor Isoform
  5. NMDA Receptor Inhibitor

NMDA Receptor Inhibitor

NMDA Receptor Inhibitors (7):

Cat. No. Product Name Effect Purity
  • HY-P0117A
    Tat-NR2B9c TFA
    Inhibitor 99.67%
    Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively.
  • HY-N0368
    Linalool
    Inhibitor ≥98.0%
    Linalool is natural monoterpene in essential olis of coriander, acts as a competitive antagonist of Nmethyl d-aspartate (NMDA) receptor, with anti-tumor, anti-cardiotoxicity activity.
  • HY-P1594A
    Dynorphin A (1-10) (TFA)
    Inhibitor 99.43%
    Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor.
  • HY-P0117
    Tat-NR2B9c
    Inhibitor
    Tat-NR2B9c (Tat-NR2Bct; NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively.
  • HY-129692
    Withanone
    Inhibitor
    Withanone is an active constituent from Withania somnifera roots with multifunctional neuroprotective effect in alleviating cognitive dysfunction.
  • HY-147873
    NMDAR/HDAC-IN-1
    Inhibitor
    NMDAR/HDAC-IN-1 (Compound 9d) is a dual NMDAR and HDAC inhibitor with a Ki of 0.59 μM for NMDAR and IC50 values of 2.67, 8.00, 2.21, 0.18 and 0.62 μM for HDAC1, HDAC2, HDAC3, HDAC6 and HDAC8, respectively.
  • HY-P1594
    Dynorphin A (1-10)
    Inhibitor
    Dynorphin A (1-10) an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor.