1. Peptides

Tat-NR2B9c 

Cat. No.: HY-P0117 Purity: 98.22%
Data Sheet SDS Handling Instructions

Tat-NR2B9c is a PSD95 inhibitor with EC50 of 7 nM, also inhibit p38. Tat-NR2B9c blocks NMDA-induced superoxide formation by prevents phosphorylation of the NOX2 p47phoxsubunit.

For research use only. We do not sell to patients.
Tat-NR2B9c Chemical Structure

Tat-NR2B9c Chemical Structure

CAS No. : 500992-11-0

Size Price Stock Quantity
10 mM * 1 mL in Water USD 731 In-stock
1 mg USD 84 In-stock
5 mg USD 216 In-stock
10 mg USD 336 In-stock
25 mg USD 660 In-stock
50 mg   Get quote  
100 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Tat-NR2B9c is a PSD95 inhibitor with EC50 of 7 nM, also inhibit p38. Tat-NR2B9c blocks NMDA-induced superoxide formation by prevents phosphorylation of the NOX2 p47phoxsubunit. target: PSD95 [1] EC 50: 7 nM [1] In vitro: Tat-NR2B9c also inhibits p38-mediated death in vitro and attenuates ROS induced by NMDAR activity. Tat-NR2B9c also prevents NMDA-induced activation of neuronal NADPH oxidase, thereby blocking superoxide production.[2] In vivo: ischemic damage in vivo

References
Molecular Weight

2518.88

Formula

C₁₀₅H₁₈₈N₄₂O₃₀

CAS No.

500992-11-0

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

H2O

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Tat-NR2B9c
Cat. No.:
HY-P0117
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