1. MAPK/ERK Pathway
  2. p38 MAPK
  3. Tat-NR2B9c TFA

Tat-NR2B9c TFA 

Cat. No.: HY-P0117A Purity: 98.99%
Handling Instructions

Tat-NR2B9c (TFA) is a 20-aa peptide, which acts as a postsynaptic density-95 (PSD-95) inhibitor, with an EC50 of 6.7 nM for PSD-95d2 (PSD-95 PDZ domain 2), and 670 nM for PSD-95d1. Tat-NR2B9c also reduces NMDA-induced p38 activation, and possesses neuroprotective efficacy.

For research use only. We do not sell to patients.

Tat-NR2B9c TFA Chemical Structure

Tat-NR2B9c TFA Chemical Structure

CAS No. : 1834571-04-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 765 In-stock
Estimated Time of Arrival: December 31
1 mg USD 84 In-stock
Estimated Time of Arrival: December 31
5 mg USD 216 In-stock
Estimated Time of Arrival: December 31
10 mg USD 336 In-stock
Estimated Time of Arrival: December 31
25 mg USD 660 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Other Forms of Tat-NR2B9c TFA:

Top Publications Citing Use of Products

    Tat-NR2B9c TFA purchased from MCE. Usage Cited in: J Cereb Blood Flow Metab. 2018 Mar 7:271678X18762637.

    Tat-NR2B9c affects PSD95-NR2B-nNOS complex and PSD95-neurexin-neuroligin complex formation after ICH. Western blots of IP with PSD95 antibody show the interactions between nNOS, NR2B, neurexin-1 or neuroligin-1, and PSD95.
    • Biological Activity

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    • References

    Description

    Tat-NR2B9c (TFA) is a 20-aa peptide, which acts as a postsynaptic density-95 (PSD-95) inhibitor, with an EC50 of 6.7 nM for PSD-95d2 (PSD-95 PDZ domain 2), and 670 nM for PSD-95d1[1]. Tat-NR2B9c also reduces NMDA-induced p38 activation, and possesses neuroprotective efficacy[2].

    IC50 & Target

    EC50: 6.7 nM (PSD-95d2), 670 nM (PSD-95d1)[1]
    p38[2]

    Storage

    -20°C, protect from light

    References
    Molecular Weight

    2632.90

    Formula

    C₁₀₇H₁₈₉F₃N₄₂O₃₂

    CAS No.

    1834571-04-8

    Sequence

    Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Leu-Ser-Ser-Ile-Glu-Ser-Asp-Val

    Sequence Shortening

    YGRKKRRQRRRKLSSIESDV

    SMILES

    OC(C(F)(F)F)=O.[YGRKKRRQRRRKLSSIESDV]

    Shipping

    Room temperature in continental US; may vary elsewhere

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    × = ×
    C1   V1   C2   V2

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    Product Name:
    Tat-NR2B9c TFA
    Cat. No.:
    HY-P0117A
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    Tat-NR2B9c TFA

    Cat. No.: HY-P0117A