1834571-04-8
Chemical Structure
Tat-NR2B9c TFA
Synonym(s): Tat-NR2Bct TFA; NA-1 TFA
- CAS No.: 1834571-04-8
- Formula:C105H188N42O30.C2HF3O2
- Molecular Weight:2632.90
SMILES: [YGRKKRRQRRRKLSSIESDV (TFA salt)]
Biological Activity: Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c TFA disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c TFA also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tat-NR2B9c TFA | 99.66% | Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c TFA disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c TFA also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy. | ||||||||||||||||||||
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Keywords
