1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
    Neuronal Signaling
  3. iGluR
  4. AMPA Receptor Isoform

AMPA Receptor

 

AMPA Receptor Related Products (43):

Cat. No. Product Name Effect Purity
  • HY-B1618
    Corticosterone
    Agonist 99.70%
    Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala).
  • HY-14608
    L-Glutamic acid
    Agonist ≥99.0%
    L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
  • HY-15067
    DNQX
    Antagonist 98.45%
    DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively).
  • HY-14608A
    L-Glutamic acid monosodium salt
    Agonist ≥98.0%
    L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
  • HY-W015309
    Decanoic acid
    Inhibitor ≥98.0%
    Decanoic acid, a component of medium chain triclycerides, is a brain-penetrant and non-competitive inhibitor of AMPA receptor.
  • HY-122150
    AMPA receptor modulator-3
    Modulator 99.57%
    AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC50: 4.4 μM).
  • HY-12505
    CX546
    Agonist 99.07%
    CX546 is a first-generation and selective benzamide-type positive AMPAR modulator.
  • HY-15079
    Talampanel
    Antagonist 98.02%
    Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity.
  • HY-10933
    CX516
    Modulator 99.50%
    CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).
  • HY-10934
    Mibampator
    Activator 99.89%
    Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors.
  • HY-12506
    Naspm
    Inhibitor
    Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
  • HY-12506A
    Naspm trihydrochloride
    Inhibitor 99.47%
    Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
  • HY-10932
    Aniracetam
    Modulator 99.89%
    Aniracetam (Ro 13-5057) is an orally active neuroprotective agent, possessing nootropics effects.
  • HY-18689
    SYM2206
    Antagonist 99.72%
    SYM2206 is a potent and non-competitive AMPA receptor antagonist, with an IC50 of 1.6 μM.
  • HY-15069
    Fanapanel
    Antagonist 99.17%
    Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively.
  • HY-14608S7
    L-Glutamic acid-d5
    Agonist ≥99.0%
    L-Glutamic acid-d5 is the deuterium labeled L-Glutamic acid.
  • HY-P2259
    TAT-GluA2 3Y
    Inhibitor 99.90%
    TAT-GluA2 3Y, an interference peptide, blocks long-term depression (LTD) at glutamatergic synapses by disrupting the endocytosis of AMPAR.
  • HY-10935
    LY450108
    Activator 99.51%
    LY450108 is a potent AMPA receptor potentiator.
  • HY-12499
    (S)-Willardiine
    Agonist 99.27%
    (S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM.
  • HY-12509
    PEPA
    Activator 99.68%
    PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.