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L-Glutamic acid

15 Cited Publications
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Based on 15 publication(s) in Google Scholar

L-Glutamic acid is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid can be used in the study of neurological diseases. L-Glutamic acid acts at ionotropic and metabotropic glutamate receptors.

For research use only. We do not sell to patients.

  • Purity: 99.96%
  • CAS No.: 56-86-0
  • Formula: C5H9NO4
  • Molecular Weight:147.13
  • Storage:

    Store at room temperature 3 years.

    In solvent   -80°C, 2 years , -20°C, 1 year
  • L-Glutamic acid Chemical Structure
    L-Glutamic acid Chemical Structure
  • Experimental Validation Results for L-Glutamic acid
  • Experimental Validation Results for L-Glutamic acid
  • Experimental Validation Results for L-Glutamic acid
  • Experimental Validation Results for L-Glutamic acid
  • Experimental Validation Results for L-Glutamic acid
  • Experimental Validation Results for L-Glutamic acid
  • Experimental Validation Results for L-Glutamic acid
CAS No.: 56-86-0
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Bio/Physico-chemical AssayWBFlow CytometryCell Proliferation/Viability AssayRT-PCRCell Imaging/Staining
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  • Cell Proliferation/Viability Assay
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  • L-Glutamic acid Chemical Structure
    L-Glutamic acid Chemical Structure
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    L-Glutamic acid purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 5:e11194. [Abstract]

    Customer Validation
     L-Glutamic acid (100 µM; 10 min) for activation of spike count. Spontaneous LFP activity is recorded from OPAB that has been pre-treated with Bicuculline and stimulated with L-Glutamic acid. The LFP signal from the activated OPAB is measured (pre), and then the electrical signal is inhibited for 10 min using a cocktail of TTX, CNQX, and AP5 and LFP was recorded again (post).

  • 1/16

    L-Glutamic acid purchased from MedChemExpress. Usage Cited in: Cancer Immunol Immunother. 2025 Jun 7;74(8):240. [Abstract]

    Customer Validation
     Flow cytometry representative image showing the effect of exogenous glutamate (1 mM) on mouse primary T cells.

  • 1/16

    L-Glutamic acid purchased from MedChemExpress. Usage Cited in: J Inflamm Res. 2025 Jan 27:18:1235-1254. [Abstract]

    Customer Validation
     Viability of HT22 cells treated with Glutamate at different concentrations (0, 5, 10, 15, 20 and 25 mM) for 24 h (n=5 at each concentration).

  • 1/16

    L-Glutamic acid purchased from MedChemExpress. Usage Cited in: J Inflamm Res. 2025 Jan 27:18:1235-1254. [Abstract]

    Customer Validation
     The relative mRNA expression levels of c-fos in the control, glu (20 mM, 24 h) and lactate groups (n=6 in each group).

  • 1/16

    L-Glutamic acid purchased from MedChemExpress. Usage Cited in: J Inflamm Res. 2025 Jan 27:18:1235-1254. [Abstract]

    Customer Validation
     Fluorescence images of TUNEL staining of HT22 cells in the control, glu (20 mM, 24 h) and lactate groups.

  • 1/16

    L-Glutamic acid purchased from MedChemExpress. Usage Cited in: J Inflamm Res. 2025 Jan 27:18:1235-1254. [Abstract]

    Customer Validation
     Images of VGLUT1 fluorescence staining in HT22 cells from the control, glu (20 mM, 24 h) and lactate groups.

  • 1/16

    L-Glutamic acid purchased from MedChemExpress. Usage Cited in: J Transl Med. 2024 Feb 18;22(1):178. [Abstract]

    Customer Validation
     PC3 and DU145 cells were treated with 10 μM glutamate for 24 h, after which the protein expression levels were analysed by western blotting. The expression intensity was normalized to that of β-tubulin (right panel).

  • L-Glutamic acid