1. Membrane Transporter/Ion Channel
    Apoptosis
    Neuronal Signaling
  2. iGluR
    Ferroptosis
    Apoptosis
  3. L-Glutamic acid monosodium salt

L-Glutamic acid monosodium salt (Synonyms: Monosodium glutamate)

Cat. No.: HY-14608A Purity: >98.0%
Handling Instructions

L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

For research use only. We do not sell to patients.

L-Glutamic acid monosodium salt Chemical Structure

L-Glutamic acid monosodium salt Chemical Structure

CAS No. : 142-47-2

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Based on 1 publication(s) in Google Scholar

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Description

L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

Clinical Trial
Molecular Weight

169.11

Formula

C₅H₈NNaO₄

CAS No.

142-47-2

SMILES

[O-]C(CC[[email protected]](N)C(O)=O)=O.[Na+]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 7.14 mg/mL (42.22 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.9133 mL 29.5666 mL 59.1331 mL
5 mM 1.1827 mL 5.9133 mL 11.8266 mL
10 mM 0.5913 mL 2.9567 mL 5.9133 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Animal Administration
[1]

For toxicity experiments, mice at PND9 (n=3-9 mice per group) are treated as follows. Two groups receive a subcutaneous (s.c.) injection of corn oil, following, 30 min later, by s.c. injection of either saline or L-Glutamic acid monosodium salt (3 g/kg); two additional groups are treated with 3,4-dihydro-2 H-pyrano[2,3-b]quinolin-7-yl-(cis-4-methoxycyclohexyl)-methanone, dissolving in corn oil (2.5 mg/kg) following, 30 min later, by a s.c. injection of either saline or L-Glutamic acid monosodium salt. In another set of experiments, four groups of crv4 mice or their wild-type littermates (n=5-7 mice per group) are injected s.c. with either saline or L-Glutamic acid monosodium salt (3 g/kg)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
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Keywords:

L-Glutamic acid monosodiumMonosodium glutamateiGluRFerroptosisApoptosisIonotropic glutamate receptorsInhibitorinhibitorinhibit

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L-Glutamic acid monosodium salt
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