1. Saccharides and Glycosides

Digitonin 

Cat. No.: HY-N4000 Purity: >50.0%
Handling Instructions

Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth.

For research use only. We do not sell to patients.

Digitonin Chemical Structure

Digitonin Chemical Structure

CAS No. : 11024-24-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
25 mg USD 50 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth.

In Vitro

Digitonin, a detergent that increases cell permeability by binding to cholesterol molecules in the cell membrane, can increase cisplatin accumulation and reduce tumour growth in vitro[1].

In Vivo

In the liver parenchyma the concentrations are of the same magnitude. Measured with the 133Xe-clearance technique, Digitonin does not alter the tumor blood flow. Digitonin enhances the tumor-growth retarding effect of CBDCA given intra-aterially at 5 mg/kg but not at 25 mg/kg[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8135 mL 4.0673 mL 8.1346 mL
5 mM 0.1627 mL 0.8135 mL 1.6269 mL
10 mM 0.0813 mL 0.4067 mL 0.8135 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

1229.31

Formula

C₅₆H₉₂O₂₉

CAS No.

11024-24-1

SMILES

C[[email protected]@]12[[email protected]]([[email protected]@H]3C)([H])[[email protected]](O[[email protected]]34CC[[email protected]@H](C)CO4)([H])[[email protected]@H](O)[[email protected]@]1([H])[[email protected]@](CC[[email protected]]5([H])[[email protected]@]6(C[[email protected]@H](O)[[email protected]](O[[email protected]]([[email protected]@H]([[email protected]@H](O)[[email protected]]7O[[email protected]@](O[[email protected]](CO)[[email protected]@H](O)[[email protected]@H]8O[[email protected]@](OC[[email protected]@H](O)[[email protected]@H]9O)([H])[[email protected]@H]9O)([H])[[email protected]@H]8O[[email protected]@](O[[email protected]](CO)[[email protected]](O)[[email protected]@H]%10O[[email protected]]([[email protected]@H]([[email protected]@H](O)[[email protected]@H]%11O)O)([H])O[[email protected]@H]%11CO)([H])[[email protected]@H]%10O)O)([H])O[[email protected]@H]7CO)C5)C)([H])[[email protected]]6([H])CC2

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: >50.0%

  • Molarity Calculator

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Product Name:
Digitonin
Cat. No.:
HY-N4000
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Digitonin

Cat. No.: HY-N4000