1. Saccharides and Glycosides
  2. Digitonin

Digitonin 

Cat. No.: HY-N4000
Handling Instructions

Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth.

For research use only. We do not sell to patients.

Digitonin Chemical Structure

Digitonin Chemical Structure

CAS No. : 11024-24-1

Size Price Stock Quantity
10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
25 mg USD 50 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

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Description

Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth.

In Vitro

Digitonin, a detergent that increases cell permeability by binding to cholesterol molecules in the cell membrane, can increase cisplatin accumulation and reduce tumour growth in vitro[1].

In Vivo

In the liver parenchyma the concentrations are of the same magnitude. Measured with the 133Xe-clearance technique, Digitonin does not alter the tumor blood flow. Digitonin enhances the tumor-growth retarding effect of CBDCA given intra-aterially at 5 mg/kg but not at 25 mg/kg[1].

Storage

4°C, stored under nitrogen

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (40.67 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8135 mL 4.0673 mL 8.1346 mL
5 mM 0.1627 mL 0.8135 mL 1.6269 mL
10 mM 0.0813 mL 0.4067 mL 0.8135 mL
*Please refer to the solubility information to select the appropriate solvent.
References
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Digitonin
Cat. No.:
HY-N4000
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Digitonin

Cat. No.: HY-N4000