142-47-2
Chemical Structure
L-Glutamic acid monosodium salt
- CAS No.: 142-47-2
- Formula:C5H8NNaO4
- Molecular Weight:169.11
IUPAC Name: sodium (S)-4-amino-4-carboxybutanoate
InChIKey: LPUQAYUQRXPFSQ-DFWYDOINSA-M
SMILES: O=C(O[Na])CC[C@H](N)C(O)=O
Biological Activity: L-Glutamic acid monosodium salt is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium salt has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium salt can be used in the study of neurological diseases. L-Glutamic acid monosodium salt acts at ionotropic and metabotropic glutamate receptors[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-Glutamic acid monosodium salt | 98.0% | L-Glutamic acid monosodium salt is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium salt has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium salt can be used in the study of neurological diseases. L-Glutamic acid monosodium salt acts at ionotropic and metabotropic glutamate receptors. | ||||||||||||||||||||
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L-Glutamic acid monosodium salt (Standard) | ≥98% | L-Glutamic acid (monosodium salt) (Standard) is the analytical standard of L-Glutamic acid (monosodium salt). This product is intended for research and analytical applications. L-Glutamic acid monosodium salt is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium salt has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium salt can be used in the study of neurological diseases. | ||||||||||||||||||||
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H-Glu(OMe)-OH | 98.0% | H-Glu(OMe)-OH is a glutamic acid derivative. | ||||||||||||||||||||
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H-Glu(OMe)-OH hydrochloride | H-Glu(OMe)-OH hydrochloride is a protonated glutamic acid derivative. | |||||||||||||||||||||
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L-Glutamic acid monosodium hydrate | 98.0% | L-Glutamic acid monosodium hydrate is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium hydrate has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium hydrate can be used in the study of neurological diseases. L-Glutamic acid monosodium hydrate acts at ionotropic and?metabotropic glutamate receptors. | ||||||||||||||||||||
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L-Glutamic acid-13C5 hydrate salt | L-Glutamic acid-13C5 hydrate salt is the 13C labeled L-Glutamic acid hydrate salt. L-Glutamic acid monosodium hydrate is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium hydrate has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium hydrate can be used in the study of neurological diseases. L-Glutamic acid monosodium hydrate acts at ionotropic and?metabotropic glutamate receptors. | |||||||||||||||||||||
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H-D-Glu(OMe)-OH | H-D-Glu(OMe)-OH is a glutamic acid derivative. | |||||||||||||||||||||
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H-DL-Glu(Ome)-OH | 98.0% | H-DL-Glu(Ome)-OH is a glutamic acid derivative. | ||||||||||||||||||||
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Sodium (S)-3-amino-3-carboxypropanoate hydrate | Sodium (S)-3-amino-3-carboxypropanoate hydrate is a biochemical assay reagent, which is utilized in bypass surgery as part of the cardioplegia solution. | |||||||||||||||||||||
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L-Glutamic acid potassium salt monohydrate | 98.0% | L-Glutamic acid potassium salt monohydrate is a glutamic acid derivative. | ||||||||||||||||||||
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Glutamic acid sodium salt | 99.92% | Glutamic acid sodium salt (Monosodium glutamate) is an orally active food flavor enhancer. Glutamic acid sodium salt causes ROS generation, mitochondrial dysfunction, and Apoptosis. Glutamic acid sodium salt upregulates CHOP, Grp78, and Bcl-2. Glutamic acid sodium salt impairs cognition, induces depressive-like behavior, induces hyperalgesia, and induces obesity and insulin resistance. Glutamic acid sodium salt can be used to study neurotoxicity (e.g., brain damage, cognitive impairment), metabolic disorders (e.g., obesity, insulin resistance), hepatotoxicity, and renal toxicity, as well as pain-related disorders. | ||||||||||||||||||||
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L-Glutamic acid monopotassium salt | 98.0% | L-Glutamic acid monopotassium salt is a food additive and flavor enhancer that can reduce the harmful effects of lithium . | ||||||||||||||||||||
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References
- [1]. Liberatore F, et al. Permissive role for mglu1 metabotropic glutamate receptors in excitotoxic retinal degeneration. Neuroscience. 2017 Sep 14. pii: S0306-4522(17)30640-1. [Content Brief]
- [2]. Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7. [Content Brief]
- [3]. Boga Pekmezekmek A, et al. L-Glutamic acid monosodium salt reduces the harmful effect of lithium on the development of Xenopus laevis embryos. Environ Sci Pollut Res Int. 2020 Nov;27(33):42124-42132. [Content Brief]
- [4]. Croce N, et al. Hydrochloric acid alters the effect of L-glutamic acid on cell viability in human neuroblastoma cell cultures. J Neurosci Methods. 2013 Jul 15;217(1-2):26-30. [Content Brief]
- [5]. Salyha N, et al. Protective role of l-glutamic acid and l-cysteine in mitigation the chlorpyrifos-induced oxidative stress in rats. Environ Toxicol Pharmacol. 2018 Dec;64:155-163. [Content Brief]