L-Glutamic acid-d3
Based on 1 Customer Validation
L-Glutamic acid-d3 is the deuterium labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
For research use only. We do not sell to patients.
- Purity: 99.12%
- CAS No.: 203805-84-9
- Formula: C5H6D3NO4
- Molecular Weight:150.15
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 203805-84-9
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Unlabeled Cas 56-86-0
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Appearance Solid
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Molecular Weight 150.15
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Formula C5H6D3NO4
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Color White to off-white
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SMILES
OC(C([2H])([2H])C[C@@](N)([2H])C(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
H2O : 10 mg/mL (66.60 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.6600 mL | 33.3000 mL | 66.6001 mL | 166.5002 mL |
| 5 mM | 1.3320 mL | 6.6600 mL | 13.3200 mL | 33.3000 mL | |
| 10 mM | 0.6660 mL | 3.3300 mL | 6.6600 mL | 16.6500 mL | |
| 15 mM | 0.4440 mL | 2.2200 mL | 4.4400 mL | 11.1000 mL | |
| 20 mM | 0.3330 mL | 1.6650 mL | 3.3300 mL | 8.3250 mL | |
| 25 mM | 0.2664 mL | 1.3320 mL | 2.6640 mL | 6.6600 mL | |
| 30 mM | 0.2220 mL | 1.1100 mL | 2.2200 mL | 5.5500 mL | |
| 40 mM | 0.1665 mL | 0.8325 mL | 1.6650 mL | 4.1625 mL | |
| 50 mM | 0.1332 mL | 0.6660 mL | 1.3320 mL | 3.3300 mL | |
| 60 mM | 0.1110 mL | 0.5550 mL | 1.1100 mL | 2.7750 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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