L-Glutamic acid-d5
Based on 1 Customer Validation
L-Glutamic acid-d5 is the deuterium labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 2784-50-1
- Formula: C5H4D5NO4
- Molecular Weight:152.16
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AMPA Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2784-50-1
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Unlabeled Cas 56-86-0
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Appearance Solid
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Molecular Weight 152.16
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Formula C5H4D5NO4
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Color White to off-white
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SMILES
OC(C([2H])([2H])C([2H])([2H])[C@@](N)([2H])C(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 14.29 mg/mL (93.91 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 7.14 mg/mL (46.92 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.5720 mL | 32.8601 mL | 65.7203 mL | 164.3007 mL |
| 5 mM | 1.3144 mL | 6.5720 mL | 13.1441 mL | 32.8601 mL | |
| 10 mM | 0.6572 mL | 3.2860 mL | 6.5720 mL | 16.4301 mL | |
| 15 mM | 0.4381 mL | 2.1907 mL | 4.3814 mL | 10.9534 mL | |
| 20 mM | 0.3286 mL | 1.6430 mL | 3.2860 mL | 8.2150 mL | |
| 25 mM | 0.2629 mL | 1.3144 mL | 2.6288 mL | 6.5720 mL | |
| 30 mM | 0.2191 mL | 1.0953 mL | 2.1907 mL | 5.4767 mL | |
| 40 mM | 0.1643 mL | 0.8215 mL | 1.6430 mL | 4.1075 mL | |
| 50 mM | 0.1314 mL | 0.6572 mL | 1.3144 mL | 3.2860 mL | |
| 60 mM | 0.1095 mL | 0.5477 mL | 1.0953 mL | 2.7383 mL | |
| 80 mM | 0.0822 mL | 0.4108 mL | 0.8215 mL | 2.0538 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Glutamic acid-d5 Related Classifications
HY-14608S7 Related Classifications
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