1358749-55-9
1358749-55-9
Chemical Structure
TAK-137
- CAS 番号: 1358749-55-9
- Formula:C19H16N2O3S
- Molecular Weight:352.41
IUPAC Name: 9-(4-phenoxyphenyl)-3,4-dihydropyrido[2,1-c][1,2,4]thiadiazine 2,2-dioxide
InChIKey: VKKLOYOLCCDGLD-UHFFFAOYSA-N
SMILES: O=S1(=O)N=C2C(=CC=CN2CC1)C=3C=CC(OC=4C=CC=CC4)=CC3
Biological Activity: TAK-137 is an AMPA receptor potentiator with weak agonistic effect. TAK-137 binds to the AMPA receptor ligand binding domain in a glutamate-dependent manner. TAK-137 potentiates AMPA-induced currents and Ca2+ influx. TAK-137 can be used for the research of neurological disease[1].
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TAK-137 | TAK-137 is an AMPA receptor potentiator with weak agonistic effect. TAK-137 binds to the AMPA receptor ligand binding domain in a glutamate-dependent manner. TAK-137 potentiates AMPA-induced currents and Ca2+ influx. TAK-137 can be used for the research of neurological disease. | |||||||||||||||||||||
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