1. MAPK/ERK Pathway
  2. Ribosomal S6 Kinase (RSK)
  3. Bupivacaine hydrochloride

Bupivacaine hydrochloride 

Cat. No.: HY-B0405A Purity: 99.32%
Handling Instructions

Bupivacaine Hydrochloride is a local anaesthetic drug belonging to the amino amide group.

For research use only. We do not sell to patients.

Bupivacaine hydrochloride Chemical Structure

Bupivacaine hydrochloride Chemical Structure

CAS No. : 18010-40-7

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Based on 1 publication(s) in Google Scholar

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Description

Bupivacaine Hydrochloride is a local anaesthetic drug belonging to the amino amide group. Target: Others Bupivacaine hydrochloride is an effective local anesthetic agent. It has a rapid onset time, a high frequency of surgical anesthesia, a long duration, and a low incidence of side effects [1]. Median doses of bupivacaine (in milligrams per kilogram) producing asystole in protocol 1 were for 17.7 for saline, 27.6 for 10% Intralipid, 49.7 for 20% Intralipid, and 82.0 for 30% Intralipid (P < 0.001 for differences between all groups). Differences in mean +/- SE concentrations of bupivacaine in plasma (in micrograms per milliliter) were significant (P < 0.05) for the difference between saline (93.3 +/- 7.6) and 30% Intralipid (212 +/- 45). In protocol 2, lipid infusion increased the dose of bupivacaine required to cause death in 50% of animals by 48%, from 12.5 to 18.5 mg/kg. The mean lipid:aqueous ratio of concentrations of bupivacaine in a plasma-Intralipid mixture was 11.9 +/- 1.77 (n = 3) [2].

Molecular Weight

324.89

Formula

C₁₈H₂₉ClN₂O

CAS No.

18010-40-7

SMILES

O=C(C1N(CCCC)CCCC1)NC2=C(C)C=CC=C2C.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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Keywords:

BupivacaineRibosomal S6 Kinase (RSK)S6KInhibitorinhibitorinhibit

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