2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. Calcium Channel
  5. L-type calcium channel Isoform

L-type calcium channel

 

L-type calcium channel Related Products (24):

Cat. No. Product Name Effect Purity
  • HY-17412
    Minocycline hydrochloride
    		Activator 99.79%
    Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic.
  • HY-B1221
    Flufenamic acid
    		Inhibitor 99.85%
    Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels.
  • HY-103311
    Ruthenium red
    		Inhibitor
    Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria.
  • HY-B1640
    Ethacrynic acid
    		Inhibitor 99.98%
    Ethacrynic acid (Etacrynic acid) is a diuretic.
  • HY-B0317
    Amlodipine
    		Antagonist 99.76%
    Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium.
  • HY-10588
    Bay K 8644
    		Agonist 98.62%
    Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644.
  • HY-N0043
    Ginsenoside Rd
    		Inhibitor 98.02%
    Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells.
  • HY-N0252
    Catharanthine
    		Inhibitor 99.76%
    Catharanthine is an alkaloid isolated from Catharanthus roseus, inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity.
  • HY-B1655
    Fluspirilene
    		Antagonist 99.66%
    Fluspirilene is a non-competitive antagonist of L-type calcium channels with an IC50 of 0.03 μM.
  • HY-14462
    NP118809
    		Inhibitor 98.79%
    NP118809 is a potent N-type calcium channel blocker, with an IC50 of 0.11 μM; also less potently inhibits L-type calcium channel with an IC50 of 12.2 μM.
  • HY-112723
    ACT-709478
    		Antagonist 99.59%
    ACT-709478 is a potent, selective, orally active, and brain penetrating T-type calcium channel blocker.
  • HY-B0768A
    Lomerizine dihydrochloride
    		Antagonist 99.84%
    Lomerizine dihydrochloride is an antagonist of L- and T-type voltagegated calcium channels.
  • HY-136909
    SR33805
    		Antagonist 99.19%
    SR33805 is a potent Ca2+ channel antagonist, with EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively.
  • HY-N7503
    Psoralenoside
    		Inhibitor 99.84%
    Psoralenoside is a benzofuran glycoside from Psoralea corylifolia.
  • HY-17611
    Etripamil
    		Antagonist 98.80%
    Etripamil (MSP-2017) is a short-acting L-type calcium-channel antagonist, can be used for the research of Paroxysmal Supraventricular Tachycardia (PSVT).
  • HY-N0252A
    Catharanthine Tartrate
    		Inhibitor 99.92%
    Catharanthine Tartrate is an alkaloid isolated from Catharanthus roseus, inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity.
  • HY-134542
    CaV1.3 antagonist-1
    		Antagonist 98.12%
    CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM.
  • HY-N2005
    Cycleanine
    		Inhibitor 99.80%
    Cycleanine is a potent vascular selective Calcium antagonist.
  • HY-17412A
    Minocycline
    		Activator
    Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic.
  • HY-B0317C
    Amlodipine mesylate
    		Antagonist
    Amlodipine mesylate, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium.