1. Anti-infection
  2. Bacterial

Minocycline hydrochloride 

Cat. No.: HY-17412 Purity: 99.61%
Data Sheet SDS Handling Instructions

Minocycline is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects.

For research use only. We do not sell to patients.
Minocycline hydrochloride Chemical Structure

Minocycline hydrochloride Chemical Structure

CAS No. : 13614-98-7

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    Minocycline hydrochloride purchased from MCE. Usage Cited in: Neurochem Res. 2017 Apr 22.

    a Statistical analysis showing the prevention effect of minocycline pretreatment (40 mg/kg/day) on CUS-, CRS- or CSDS-induced decreases in hippocampal microglial numbers. b, c Statistical analysis showing the prevention effect of minocycline pretreatment (40 mg/kg/day) on CUS-, CRS- or CSDS-induced increases in the immobile time in the TST (b) and FST (c).
    • Biological Activity

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    Description

    Minocycline is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects. IC50 Value: N/A Target: Antibacterial Minocycline acts as a matrix metalloproteinase (MMP) inhibitor; attenuates disease severity in mouse models of multiple sclerosis. Minocycline also inhibit the enzymatic activity of poly(ADP-ribose) polymerase-1 (PARP-1) and angiogenesis. In addition, Minocycline is suggested to down-regulate CD40L on T cells and inhibit the replication of SIV and HIV. Orally active and brain penetrant.

    Clinical Trial
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    References
    Molecular Weight

    493.94

    Formula

    C₂₃H₂₈ClN₃O₇

    CAS No.

    13614-98-7

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Shipping

    Room temperature in continental US; may vary elsewhere

    Solvent & Solubility

    H2O: 2.45 mg/mL; DMSO: 0.49 mg/mL

    * "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

    Purity: 99.61%

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    Product Name:
    Minocycline hydrochloride
    Cat. No.:
    HY-17412
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