88150-42-9
Chemical Structure
Amlodipine
- CAS No.: 88150-42-9
- Formula:C20H25ClN2O5
- Molecular Weight:408.88
IUPAC Name: 3-ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey: HTIQEAQVCYTUBX-UHFFFAOYSA-N
SMILES: O=C(OCC)C1=C(NC(C)=C(C1C2=CC=CC=C2Cl)C(OC)=O)COCCN
Biological Activity: Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer[1][2][3].
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Amlodipine | 99.87% | Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer. | ||||||||||||||||||||
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Amlodipine (Standard) | ≥98% | Amlodipine (Standard) is the analytical standard of Amlodipine. This product is intended for research and analytical applications. Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer. | ||||||||||||||||||||
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Amlodipine-d4 | 98.46% | Amlodipine-d4 is a deuterium labeled Amlodipine (HY-B0317). Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer. | ||||||||||||||||||||
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Similarity Score 1.00
HY-14744Levamlodipine -
Similarity Score 1.00
HY-14744SLevamlodipine-d4 -
Similarity Score 1.00
HY-B0317D(R)-Amlodipine -
Similarity Score 1.00
HY-B0317DS(R)-Amlodipine-d4 -
Similarity Score 0.98
HY-14744BLevamlodipine hydrochloride -
Similarity Score 0.98
HY-14744CLevamlodipine hydrobromide -
Similarity Score 0.98
HY-B0317FAmlodipine hydrochloride -
Similarity Score 0.92
HY-W292468Amlodipine impurity 3 -
Similarity Score 0.92
HY-B0317CAmlodipine mesylate -
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References
- [1]. Kishen G. Bulsara, et al. Amlodipine.
- [2]. Haria M, et al. Amlodipine. A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disease [published correction appears in Drugs 1995 Nov;50(5):896]. Drugs. 1995;50(3):560-586. [Content Brief]
- [3]. Yoshida J, et, al. Antitumor effects of amlodipine, a Ca2+ channel blocker, on human epidermoid carcinoma A431 cells in vitro and in vivo. Eur J Pharmacol. 2004 May 25;492(2-3):103-12. [Content Brief]
