1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. Calcium Channel
  3. Levamlodipine

Levamlodipine (Synonyms: (S)-Amlodipine; Levoamlodipine)

Cat. No.: HY-14744
Handling Instructions

Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina.

For research use only. We do not sell to patients.

Levamlodipine Chemical Structure

Levamlodipine Chemical Structure

CAS No. : 103129-82-4

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Description

Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].

IC50 & Target

Calcium channel[1].

Molecular Weight

408.88

Formula

C₂₀H₂₅ClN₂O₅

CAS No.

103129-82-4

SMILES

O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)[[email protected]@H]1C2=CC=CC=C2Cl)OCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (244.57 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4457 mL 12.2285 mL 24.4571 mL
5 mM 0.4891 mL 2.4457 mL 4.8914 mL
10 mM 0.2446 mL 1.2229 mL 2.4457 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.11 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.11 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Levamlodipine(S)-AmlodipineLevoamlodipineCalcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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Product Name:
Levamlodipine
Cat. No.:
HY-14744
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