1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. MMP
  4. ADAM17 Isoform

ADAM17

 
Cat. No. Product Name Effect Purity
  • HY-10293
    Aderbasib
    Inhibitor 98.09%
    Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17.
  • HY-115670
    GW280264X
    Inhibitor
    GW280264X is the mixed ADAM10/TACE (ADAM17) metalloproteinases inhibitor.
  • HY-101448
    TMI-1
    Inhibitor 99.59%
    TMI-1 is a potent inhibitor of disintegrin metalloenzyme 17 (ADAM17) and other MMPs.
  • HY-120852
    JG26
    Inhibitor
    JG26 is an ADAM17 inhibitor, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM for ADAM8, ADAM17, ADAM10 and MMP-12, respectively.
Cat. No. Product Name / Synonyms Species Source