1. GPCR/G Protein
  2. Glucocorticoid Receptor
  3. Prednisone

Prednisone (Synonyms: Dehydrocortisone)

Cat. No.: HY-B0214 Purity: 99.35%
Handling Instructions

Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.

For research use only. We do not sell to patients.

Prednisone Chemical Structure

Prednisone Chemical Structure

CAS No. : 53-03-2

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10 mM * 1 mL in DMSO USD 79 In-stock
Estimated Time of Arrival: December 31
1 g USD 72 In-stock
Estimated Time of Arrival: December 31
5 g USD 180 In-stock
Estimated Time of Arrival: December 31
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Description

Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound. Target: Others Prednisone is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant drug. It is used to treat certain inflammatory diseases (such as moderate allergic reactions) and (at higher doses) some types of cancer, but has significant adverse effects. Because it suppresses the immune system, it leaves patients more susceptible to infections. Prednisone can also be used in the treatment of decompensated heart failure to potentiate renal responsiveness to diuretics, especially in heart failure patients with refractory diuretic resistance with large dose of loop diuretics. The mechanism is prednisone, as a glucocorticoid, can improve renal responsiveness to atrial natriuretic peptide by increasing the density of natriuretic peptide receptor type A in the renal inner medullary collecting duct, inducing a potent diuresis.

Clinical Trial
Molecular Weight

358.43

Formula

C₂₁H₂₆O₅

CAS No.

53-03-2

SMILES

C[[email protected]@]1(C2)[[email protected]](C(CO)=O)(O)CC[[email protected]@]1([H])[[email protected]]3([H])CCC4=CC(C=C[[email protected]]4(C)[[email protected]@]3([H])C2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 150 mg/mL (418.49 mM)

*"≥" means soluble, but saturation unknown.

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7899 mL 13.9497 mL 27.8995 mL
5 mM 0.5580 mL 2.7899 mL 5.5799 mL
10 mM 0.2790 mL 1.3950 mL 2.7899 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.35%

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Prednisone
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