53-03-2
53-03-2
Chemical Structure
Prednisone
Synonym(s): Dehydrocortisone
- CAS No.: 53-03-2
- Formula:C21H26O5
- Molecular Weight:358.43
IUPAC Name: (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthrene-3,11(6H)-dione
InChIKey: XOFYZVNMUHMLCC-ZPOLXVRWSA-N
SMILES: C[C@@]1(C2)[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])C2=O)=O
Biological Activity: Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus[1][2].
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Prednisone | 99.99% | Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus. | ||||||||||||||||||||
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Prednisone (Standard) | 99.81% | Prednisone (Standard) is the analytical standard of Prednisone. This product is intended for research and analytical applications. Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus. | ||||||||||||||||||||
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Prednisone-d4 | Prednisone-d4 is deuterated labeled Prednisone (HY-B0214). Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus. | |||||||||||||||||||||
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Prednisone-d7 | Prednisone-d7 (Dehydrocortisone-d7) is deuterium labeled Prednisone. Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus. | |||||||||||||||||||||
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Prednisone-d8 | Prednisone-d8 is the deuterium labeled Prednisone. Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound. | |||||||||||||||||||||
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Prednisone-13C2,d2 | Prednisone-13C2,d2 (Dehydrocortisone-13C2,d2) is 13C labeled Prednisone. Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus. | |||||||||||||||||||||
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Prednisone 21-aldehyde | Prednisone 21-aldehyde is a biochemical reagent. | |||||||||||||||||||||
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Cortisone | 99.34% | Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations. | ||||||||||||||||||||
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Cortisone-13C3 | Cortisone-13C3 is the 13C-labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations. | |||||||||||||||||||||
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Prednisolone (Standard) | 99.48% | Prednisolone (Standard) is the analytical standard of Prednisolone. This product is intended for research and analytical applications. Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research. | ||||||||||||||||||||
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Meprednisone | 99.59% | Meprednisone is a glucocorticoid and a methylated derivative of Prednisone (HY-B0214). Meprednisone modulates glucocorticoid receptor. Meprednisone is orally active. | ||||||||||||||||||||
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Prednisone acetate | 99.92% | Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response. | ||||||||||||||||||||
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Methylprednisolone impurity 2 | Methylprednisolone impurity 2 is an impurity of Methylprednisolone. | |||||||||||||||||||||
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16α-Hydroxy-11-keto prednisolone | 16α-Hydroxy-11-keto prednisolone (compound M-X) is a metabolite of Budesonide (HY-13580). Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide is a widely used for study of asthma, rhinitis, and inflammatory bowel disease. | |||||||||||||||||||||
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Betamethasone impurity 7 | Betamethasone impurity 7 is an impurity of Betamethasone. | |||||||||||||||||||||
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Methylprednisolone acetate impurity 9 | 99.36% | Methylprednisolone acetate impurity 9 (6alpha-Methyl Prednisone 21-Acetate) is an impurity of Methylprednisolone acetate. | ||||||||||||||||||||
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References
- [1]. RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1(4):488-96. [Content Brief]
- [2]. [2]N Tomioka, et al. Effects of prednisolone on acute viral myocarditis in mice. J Am Coll Cardiol. 1986 Apr;7(4):868-72. [Content Brief]
