1. Metabolic Enzyme/Protease
    Membrane Transporter/Ion Channel
  2. Gutathione S-transferase
    P-glycoprotein
  3. Coniferyl ferulate

Coniferyl ferulate 

Cat. No.: HY-N1916
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Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis, reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM.

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Coniferyl ferulate Chemical Structure

Coniferyl ferulate Chemical Structure

CAS No. : 63644-62-2

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Description

Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis, reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM[1].

IC50 & Target

Glutathione S-transferase[1]
P-glycoprotein[1]

Molecular Weight

356.37

Formula

C₂₀H₂₀O₆

CAS No.

63644-62-2

SMILES

O=C(OC/C=C/C1=CC=C(O)C(OC)=C1)/C=C/C2=CC=C(O)C(OC)=C2

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Keywords:

Coniferyl ferulateGutathione S-transferaseP-glycoproteinGlutathione transferasesGSTsP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243Inhibitorinhibitorinhibit

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Coniferyl ferulate
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