PBCRBS Traditional Chinese Medicine Compound Library

83 Cited Publications
Customer Review

Based on 83 publication(s) in Google Scholar

Since ancient times, promoting blood circulation for removing blood stasis (PBCRBS) has been one of the most popular research contents in the area of traditional Chinese medicine (TCM) and integrated medicine. Rhizoma, Persicae Semen, Carthami Flos, Curcumae Longae Rhizoma and so on are common TCM with PBCRBS characteristic. Studies have shown that the mechanism of action of PBCRBS TCM is to promote blood circulation (improving cardiovascular and cerebrovascular functions, physical and chemical properties of blood, platelet and coagulation system and other physiological functions) and remove blood stasis (anti-myocardial ischemia, cerebral ischemia, inhibition of platelet aggregation, anti-coagulation, anti-thrombosis, etc.). Not only that, PBCRBS TCM has anti-infection, inhibit inflammation, regulate immune function, inhibit immune response, inhibit abnormal tissue proliferation and other functions. Therefore, PBCRBS TCM has high research value in all- field disease research fields.

MCE can supply 1,006 monomer component from more than a hundred sources of PBCRBS TCM, which can be used in TCM studies, drug development and mechanism-based studies.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Service

Description & Advantages

•   A unique collection of 1,006 PBCRBS Traditional Chinese Medicine for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of compounds for diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 1,006 PBCRBS Traditional Chinese Medicine supplied as pre-dissolved Solutions or Solid.

Solution: 972 compounds supplied in 10 mM solution, 27 compounds supplied in 2 mM solution, 7 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage
-80°C
Shipping
Blue ice or dry ice

Documentation

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Composition

Apoptosis (243)

Bacterial (151)

Autophagy (109)

NF-κB (103)

Fungal (64)

p38 MAPK (58)

Akt (56)

COX (55)

Parasite (47)

PI3K (43)

Keap1-Nrf2 (38)

Caspase (37)

ERK (33)

JNK (32)

PPAR (24)

MMP (22)

Antibiotic (21)

STAT (21)

AMPK (19)

Amyloid-β (18)

HIV (17)

mTOR (16)

Tyrosinase (15)

JAK (14)

Mitophagy (12)

HSV (11)

SARS-CoV (11)

PKC (9)

SOD (9)

Sirtuin (8)

EGFR (7)

iGluR (7)

nAChR (7)

PARP (7)

VEGFR (7)

FXR (6)

PERK (6)

Wnt (6)

AP-1 (5)

CDK (5)

FGFR (5)

GLUT (5)

GSK-3 (5)

mAChR (5)

PKA (5)

Amylases (4)

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200 mg
USD 120
In-stock
Estimated to ship on August 31 More
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
Estimated to ship on August 31 More